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呼吸运动校正技术在减小肝脏CT灌注成像参数测量误差中的作用
其他题名Evaluation of a breath-motion-correction technique in reducing measurement error in hepatic CT perfusion imaging
何为; 刘剑羽; 李剑颖; 廖静敏; 李选
关键词体层摄影术 X线计算机 灌流 Tomography X-ray Computed Perfusion
刊名中华放射学杂志
2009
DOI10.3760/cma.j.issn.1005-1201.2009.12.007
43期:12页:1260-1263
收录类别中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型Journal Article
摘要目的 评价呼吸运动校正技术对于减小肝脏CT灌注成像中时间-密度曲线(TDC)参数测量误差的作用.方法 前瞻性应用64层CT扫描仪对25例临床怀疑肝脏病变的患者行肝门部灌注扫描.对门静脉右支主干所在层面进行呼吸运动校正,分别在校正前后门静脉右支主干内选取10个ROI并绘制TDC,记录达峰时间及峰值,计算各例校正前后达峰时间和峰值的平均值、标准差及变异系数.应用两配对样本秩和检验比较校正前后达峰时间和峰值变异系数的差异,应用独立样本t检验比较校正前后峰值均值的差异.结果 经呼吸运动校正后门静脉右支主干TDC峰值变异系数的中位数(四分位距)为2.84%(2.10%,4.57%),小于校正前5.19%(3.90%,7.27%),差异有统计学意义(Z=-3.108,P<0.01).校正后达峰时间变异系数的中位数为2.64%(0.76%,4.41%),亦小于校正前5.23%(3.81%,7.43%),差异有统计学意义(Z=-3.924,P<0.01).8例门静脉右支主干TDC峰值校正前后差异有统计学意义(P<0.05),且校正后峰值均大于校正前.结论 呼吸运动校正技术可有效减小肝脏CT灌注成像中TDC参数测量的随机误差. Objective To evaluate the effect of a breath-motion-correction (BMC) technique in reducing measurement error of the time-density curve (TDC) in hepatic CT perfusion imaging.Methods Twenty-five patients with suspected liver diseases underwent hepatic CT perfusion scans.The right branch of portal vein was selected as the anatomy of interest and performed BMC to realign image slices for the TDC according to the rule of minimizing the temporal changes of overall structures.Ten ROIs was selected on the right branch of portal vein to generate 10 TDCs each with and without BMC.The values of peak enhancement and the time-to-peak enhancement for each TDC were measured.The coefficients of variation (CV) of peak enhancement and the time-to-peak enhancement were calculated for each patient with and without BMC.Wilcoxon signed ranks test was used to evaluate the difference between the CV of the two parameters obtained with and without BMC.Independent-samples t test was used to evaluate the difference between the values of peak enhancement obtained with and without BMC. Results The median (quartiles) of CV of peak enhancement with BMC [2.84% (2.10%,4.57%)]was significantly lower than that without BMC [5.19% (3.90%,7.27%)](Z=-3.108,P< 0.01).The median (quartiles) of CV of time-to-peak enhancement with BMC [2.64% (0.76%,4.41%)]was significantly lower than that without BMC [5.23% (3.81%,7.43%)](Z=-3.924,P<0.01).In 8 cases,TDC demonstrated statistically significant higher peak enhancement with BMC (P< 0.05).Conclusion By applying the BMC technique we can effectively reduce measurement error for parameters of the TDC in hepatic CT perfusion imaging.
语种中文
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文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/69420
专题北京大学第三临床医学院_放射科
作者单位1.北京大学第三医院放射科,100191
2.GE中国CT影像研究中心
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GB/T 7714
何为,刘剑羽,李剑颖,等. 呼吸运动校正技术在减小肝脏CT灌注成像参数测量误差中的作用[J]. 中华放射学杂志,2009,43(12):1260-1263.
APA 何为,刘剑羽,李剑颖,廖静敏,&李选.(2009).呼吸运动校正技术在减小肝脏CT灌注成像参数测量误差中的作用.中华放射学杂志,43(12),1260-1263.
MLA 何为,et al."呼吸运动校正技术在减小肝脏CT灌注成像参数测量误差中的作用".中华放射学杂志 43.12(2009):1260-1263.
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