北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第三临床医学院  > 放射科  > 期刊论文
学科主题: 放射科学
题名:
呼吸运动校正技术在减小肝脏CT灌注成像参数测量误差中的作用
其他题名: Evaluation of a breath-motion-correction technique in reducing measurement error in hepatic CT perfusion imaging
作者: 何为; 刘剑羽; 李剑颖; 廖静敏; 李选
关键词: 体层摄影术 ; X线计算机 ; 灌流 ; Tomography ; X-ray computed ; Perfusion
刊名: 中华放射学杂志
发表日期: 2009
DOI: 10.3760/cma.j.issn.1005-1201.2009.12.007
卷: 43, 期:12, 页:1260-1263
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的 评价呼吸运动校正技术对于减小肝脏CT灌注成像中时间-密度曲线(TDC)参数测量误差的作用.方法 前瞻性应用64层CT扫描仪对25例临床怀疑肝脏病变的患者行肝门部灌注扫描.对门静脉右支主干所在层面进行呼吸运动校正,分别在校正前后门静脉右支主干内选取10个ROI并绘制TDC,记录达峰时间及峰值,计算各例校正前后达峰时间和峰值的平均值、标准差及变异系数.应用两配对样本秩和检验比较校正前后达峰时间和峰值变异系数的差异,应用独立样本t检验比较校正前后峰值均值的差异.结果 经呼吸运动校正后门静脉右支主干TDC峰值变异系数的中位数(四分位距)为2.84%(2.10%,4.57%),小于校正前5.19%(3.90%,7.27%),差异有统计学意义(Z=-3.108,P<0.01).校正后达峰时间变异系数的中位数为2.64%(0.76%,4.41%),亦小于校正前5.23%(3.81%,7.43%),差异有统计学意义(Z=-3.924,P<0.01).8例门静脉右支主干TDC峰值校正前后差异有统计学意义(P<0.05),且校正后峰值均大于校正前.结论 呼吸运动校正技术可有效减小肝脏CT灌注成像中TDC参数测量的随机误差. Objective To evaluate the effect of a breath-motion-correction (BMC) technique in reducing measurement error of the time-density curve (TDC) in hepatic CT perfusion imaging.Methods Twenty-five patients with suspected liver diseases underwent hepatic CT perfusion scans.The right branch of portal vein was selected as the anatomy of interest and performed BMC to realign image slices for the TDC according to the rule of minimizing the temporal changes of overall structures.Ten ROIs was selected on the right branch of portal vein to generate 10 TDCs each with and without BMC.The values of peak enhancement and the time-to-peak enhancement for each TDC were measured.The coefficients of variation (CV) of peak enhancement and the time-to-peak enhancement were calculated for each patient with and without BMC.Wilcoxon signed ranks test was used to evaluate the difference between the CV of the two parameters obtained with and without BMC.Independent-samples t test was used to evaluate the difference between the values of peak enhancement obtained with and without BMC. Results The median (quartiles) of CV of peak enhancement with BMC [2.84% (2.10%,4.57%)]was significantly lower than that without BMC [5.19% (3.90%,7.27%)](Z=-3.108,P< 0.01).The median (quartiles) of CV of time-to-peak enhancement with BMC [2.64% (0.76%,4.41%)]was significantly lower than that without BMC [5.23% (3.81%,7.43%)](Z=-3.924,P<0.01).In 8 cases,TDC demonstrated statistically significant higher peak enhancement with BMC (P< 0.05).Conclusion By applying the BMC technique we can effectively reduce measurement error for parameters of the TDC in hepatic CT perfusion imaging.
语种: 中文
原文出处: 查看原文
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/69420
Appears in Collections:北京大学第三临床医学院_放射科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.北京大学第三医院放射科,100191
2.GE中国CT影像研究中心

Recommended Citation:
何为,刘剑羽,李剑颖,等. 呼吸运动校正技术在减小肝脏CT灌注成像参数测量误差中的作用[J]. 中华放射学杂志,2009,43(12):1260-1263.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[何为]'s Articles
[刘剑羽]'s Articles
[李剑颖]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[何为]‘s Articles
[刘剑羽]‘s Articles
[李剑颖]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace