北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第三临床医学院  > 放射科  > 期刊论文
学科主题: 放射科学
题名:
延迟Gd-DTPA增强MR软骨成像:全关节软骨成像的可行性分析
其他题名: Full-Joint Coverage Delayed Gadolinium-Enhanced MRI of Cartilage:Preliminary Study in Vitro
作者: 郑卓肇; 李洁; 李选
关键词: 磁共振成像 ; 软骨,关节 ; 钆喷替酸葡甲胺 ; Magnetic resonance imaging ; cartilage,anticular ; gadopentetate dimeglumine
刊名: 中国医学影像学杂志
发表日期: 2010
DOI: 10.3969/j.issn.1005-5185.2010.01.006
卷: 18, 期:1, 页:14-18
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的:探讨多层IR-TSE和可变翻转角三维FLASH序列实现全关节软骨t1值测量的可行性.材料和方法:针对模型(不同浓度的稀释Gd-DTPA溶液)和离体牛软骨,分别利用多层IR-TSE和可变翻转角三维FLASH序列进行t1值测量.以单层IR-TSE测量结果为参照标准,验证上述两种技术的可行性.结果:在模型中,多层IR-TSE与单层IR-TSE测量值的相关系数为1.000(P<0.001);三维FLASH与单层IR-TSE测量值的相关系数为0.997(P<0.001).在离体牛软骨延迟钆增强MR软骨成像中,单层IR-TSE、多层IR-TSE和三维FLASH均显示胰蛋白酶处理侧软骨的t1值显著低于对照侧软骨.多层IR-TSE与单层IR-TSE相比较,对照侧、处理侧和总体软骨t1值的相关系数分别为0.821(P=0.012)、0.968(P=0.001)和0.953(P=0.001);三维FLASH与单层IR-TSE相比较,对照侧、处理侧和总体软骨t1值的相关系数分别为0.199(P=0.637)、0.757(P=0.030)和0.755(P=0.001).结论:多层IR-TSE和可变翻转角三维FLASH序列均可用于全关节软骨的t1值测量. Purpose To investigate the feasibility of T1 measurement using multi-slice inversion recovery turbo spin echo (IR-TSE) and variable flip angle three-dimensional fast low angle shot (3D FLASH) for full-joint coverage delayed gadolinium enhanced MRI of the cartilage. Materials and Methods MR phantoms using dilated gadolinium solution with different concentrations and ex vivo bovine cartilages were scanned using multi-slice IR-TSE and variable flip angle 3D FLASH sequences and the T1 values were calculated. The referring T1 value were obtained using single slice IR-TSE sequence. Results On phantom study, the correlation coefficiencies between multi-slice IR-TSE, 3D FLASH sequences and single slice IR-TSE was 1.000 and 0.997, respectively, where P<0.001 on ex vivo bovine cartilage study, the T1 values of the trypsin degraded species measured by single-slice, multi-slice IR-TSE and 3D-FLASH were significantly lower than the control species. The correlation coefficiency between single-slice and multi-slice IR-FSE on the control group, the trypsin degraded group and both was 0.821(P=0.012), 0.968(P=0.001), and 0.953(P=0.001) respectively. The correlation coefficiency between single-slice IR-FSE and 3D-FLASH on the trypsin degraded group, control group and both was 0.199(P=0.637), 0.757(P=0.030), and 0.775(P=0.001) respectively, where P<0.001. Conclusion Both Multi-slice IR-TSE and variable flip angle 3D-FLASH sequences can be applied for T1 measurement of the full joint cartilage.
语种: 中文
原文出处: 查看原文
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/69523
Appears in Collections:北京大学第三临床医学院_放射科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 北京大学第三医院放射科 北京 100191

Recommended Citation:
郑卓肇,李洁,李选. 延迟Gd-DTPA增强MR软骨成像:全关节软骨成像的可行性分析[J]. 中国医学影像学杂志,2010,18(1):14-18.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[郑卓肇]'s Articles
[李洁]'s Articles
[李选]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[郑卓肇]‘s Articles
[李洁]‘s Articles
[李选]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace