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IR@PKUHSC  > 北京大学第三临床医学院  > 放射科  > 期刊论文
学科主题: 放射科学
题名:
菲立磁增强MRI在肝脏局灶性病变诊断中的价值
其他题名: Evaluation of Feridex-enhanced MRI in the Diagnosis of Focal Hepatic Lesions
作者: 刘剑羽; 谢敬霞; 姚学会; 韩鸿宾; 郑卓肇
关键词: 超顺磁性氧化铁 ; 肝脏 ; 磁共振成像
刊名: 临床放射学杂志
发表日期: 2001
DOI: 10.3969/j.issn.1001-9324.2001.04.004
卷: 20, 期:4, 页:256-258
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的评价菲立磁增强MRI在肝脏实性占位性病变诊断中的应用价值。材料与方法对21例怀疑有肝脏局灶性占位病变患者行MR平扫及菲立磁增强MRI检查。扫描序列包括频率选择脂肪抑制及非脂肪抑制HASTE T2WI、True FISP T2*WI、频率选择脂肪抑制FLASH T1WI。比较增强前后T2WI及T2*WI病灶及肝脏的信噪比(SNR)及对比噪声比(CNR);观察增强前后病灶数量及形态;结合MR平扫及增强MRI表现进行定性诊断。结果菲立磁增强T2WI及T2*WI肝脏信号强度较平扫明显下降,病灶与肝脏的CNR较平扫明显提高,差异具有统计学意义。结论菲立磁增强T2WI及T2*WI可明显提高肝脏实性占位性病灶的检出率。菲立磁增强T1WI在肝脏局灶性病变的定性诊断中具有潜在价值,有待于进一步开发与研究。 Objective To evaluate Feridex (superparamagnetic iron oxide, SPIO) enhanced MRI in the diagnosis of hepatic focal solid lesions. Materials and Methods Plain and Feridex-enhanced MRI were performed in 21 patients with suspected focal hepatic lesions. The enhanced-MRI scanning started at 60min. After intravenous infusion of 10μmol/kg of Feridex. The effect of Feridex on signal intensity of the liver, CNR of lesion vs liver were assessed with quantitative analysis. Results Compared with plain scan, signal intensity of liver on Feridex-enhanced T2WI was significantly decreased and CNRs of lesion vs liver were significantly improved. Conclusion The defection of focal lesions in liver can be significantly with Feridex-enhanced T2WI and T2*WI. Feridex-enhanced T2WI is very useful for the diagnosis of focal hepatic lesions and Feridex-enhanced T1WI has potential for qualitative diagnosis of focal hepatic lesions.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/69613
Appears in Collections:北京大学第三临床医学院_放射科_期刊论文

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作者单位: 北京大学第三医院放射科

Recommended Citation:
刘剑羽,谢敬霞,姚学会,等. 菲立磁增强MRI在肝脏局灶性病变诊断中的价值[J]. 临床放射学杂志,2001,20(4):256-258.
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