目的 了解医院外科重症监护病房(ICU)医院感染病原菌情况及耐药情况.方法 对医院外科ICU 2008年4月-2009年3月发生医院感染的病原菌来源及耐药性进行统计分析.结果 在770例患者中,发生医院感染116例,感染率为15.06%;共检测出病原菌226株,以革兰阴性菌为主,占63.27%,其中鲍氏不动杆菌对绝大多数药物的耐药率>70.00%;革兰阳性菌以金黄色葡萄球菌为主,占所有病原菌的20.35%,耐甲氧西林金黄色葡萄球菌检出率为41.3%,但对万古霉素和利奈唑胺的敏感率为100.00%.结论 为控制细菌耐药性的发展,减少多药耐药菌的感染,必须加强抗菌药物的合理使用及消毒隔离工作.
OBJECTIVE To investigate the distribution and drug resistance of nosocomial infection pathogens.METHODS The data of pathogen's origin and antibacterial resistance of Intensive Care Unit (ICU) inpatients from Apr 2008 to Mar 2009 in a Hospital were analyzed. RESULTS There were 226 strains pathogens isolated from 116 nosocomial infection cases, from which the Gram-negative bacteria were predominate (63.27%). The resistance rates of Acinetobacter baumannii was the highest in Gram-negative bacteria, more than 70% isolates resistant to almost antibacterial. The main Gram-positive bacteria were Staphylococcus aureus, and the rate of meticillin-resistant S. aureus (MRSA) was 41.3%. All S. aureus were sensitive to vaneomycin and Linezolid.CONCLUSIONS To control the antibacterial resistance of pathogens and decrease the nosocomial infection, it is important to strengthen the appropriate use of antibiotics.