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学科主题: 呼吸内科学
题名:
支气管舒张试验判定指标的诊断价值
其他题名: Diagnostic value of various pulmonary function standards of bronchodilation test
作者: 梅静静; 陈亚红; 王新茂; 梁岩静; 柳晓芳
关键词: 支气管舒张试验 ; 肺功能指标 ; 诊断价值 ; Bronchodilatation test ; Pulmonary function standards ; Diagnostic value
刊名: 国际呼吸杂志
发表日期: 2014
DOI: 10.3760/cma.j.issn.1673-436X.2014.03.010
卷: 34, 期:3, 页:196-199
收录类别: 中国科技核心期刊
文章类型: Journal Article
摘要: 目的 研究相关肺功能指标在支气管舒张试验中的诊断价值.方法 收集北京大学第三医院门诊肺功能室1044例患者的肺功能资料,以临床常用标准FEV1标准为参照,评估FVC,呼气峰流速(PEF),用力呼气流速25%-75%(FEF25%-75%)对支气管舒张试验的诊断价值.结果 应用支气管舒张剂后,FEV1,FVC,PEF,FEF25%-75%的阳性率分别为26.7%,21.8%,21.8%,34.0%,以FEV1标准为参照,FVC,PEF,FEF25 %%-75%等三项标准的灵敏度分别为53.0%,49.5%,97.8%,特异度分别为89.5%,88.2%,83.8%,阳性预测值分别为64.9%,60.5%,68.8%,阴性预测值分别为83.9%,82.7%,99.1%,ROC曲线下面积分别为0.866,0.798,0.979,Kappa值分别为0.45,0.40,0.72.结论 支气管舒张试验应以FEV1作为主要标准,并联合其他多项肺功能指标及临床资料加以综合评价. Objective To evaluate the diagnostic value of various pulmonary function standards of diagnosing on bronchodilation test.Methods The lung function test results of 1 044 patients in Peking university third hospital were collected,and compared with FEV1 criterion as reference,the diagnostic value of FVC,PEF and FEF25%-75% on bronchodilation test were estimated.Results The positive rate of FEV1,FVC,PEF and FEF25%-75% were respectively 26.7%,21.8%,21.8% and 34.0%.Jarging by FEV1 as objective reference,the sensitivity of FVC,PEF and FEF25%-75% were 53.0%,49.5% and 97.8% respectively,the specificity of them were 89.5 %,88.2 % and 83.8 %,the positive predictive value of them were 64.9%,60.5%,68.8%,the negative predictive value of them were 83.9%,82.7%,99.1%,the area under the ROC curve of them were separately 0.866,0.798 and 0.979,and the Kappa statistic of FVC,PEF and FEF25%-75% were 0.45,0.40 and 0.72 respectively.Conclusions FEV1 should be used as the primary standard in assessing bronchodilator reversibility,and other standards and clinical features are also important for evaluating the results of bronchodilatation test.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/71059
Appears in Collections:北京大学第三临床医学院_呼吸内科_期刊论文

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作者单位: 100191,北京大学第三医院呼吸科

Recommended Citation:
梅静静,陈亚红,王新茂,等. 支气管舒张试验判定指标的诊断价值[J]. 国际呼吸杂志,2014,34(3):196-199.
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