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学科主题: 呼吸内科学
题名:
慢性阻塞性肺疾病患者深吸气量与生命质量的关系
其他题名: Correlation of the quality of life with the inspiratory capacity in patients with chronic obstructive pulmonary disease
作者: 沈宁; 姚婉贞; 刘政; 王筱宏; 郝振婷; 柳小芳
关键词: 肺疾病,慢性阻塞性 ; 问卷调查 ; 呼吸功能试验 ; 吸气量 ; Pulmonary disease,chronic obstructive ; Questionnaires ; Respiratory function tests ; Inspiratory capacity
刊名: 中华结核和呼吸杂志
发表日期: 2010
DOI: 10.3760/cma.j.issn.1001-0939.2010.04.008
卷: 33, 期:4, 页:261-264
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的 探讨COPD患者深吸气量等肺功能指标与生命质量的关系.方法 2006年1月至2007年3月北京大学第三医院门诊的COPD稳定期患者62例,其中男55例,女7例;年龄43~79岁,平均年龄(66±8)岁.均进行肺容量、肺通气功能和小气道功能检查,并经圣乔治呼吸问卷(SGRQ)评分,采用Pearson直线相关分析SGRQ的分值与总分、SGRQ评分与肺功能指标之间的相关性.结果 62例COPD稳定期患者的SGRQ总分为(43±17)分,其中呼吸症状分值为(54±23)分,活动受限分值为(54±19)分,疾病影响分值为(33±20)分;肺功能检查结果中FEV_1占预计值%为(43±13)%,FEV_1/FVC为(52±11)%,残气量占预计值%为(194±50)%,残气量/肺总量为(166±31)%,深吸气量占预计值%为(74±21)%.深吸气量占预计值%、残气量占预计值%、残气量/肺总量、FEV,占预计值%、FEV./FVC、呼气峰流量、用力呼出50%肺活量时呼气流量(FEF_(50%))、用力呼出25%肺活量时呼气流量(FE_(25%))和最大呼气中段流量(MMEF)与SGRQ总分均呈负相关,其中通气功能指标的相关系数为-0.336~-0.479,小气道功能指标的相关系数为-0.368~-0.411,而深吸气量占预计值%和SGRQ的3个能区分值和总分相关性最好,相关系数为-0.418~-0.521,均P<0.05.SGRQ的3个能区分值中呼吸症状和肺功能无显著相关性.结论 肺功能检查中肺容量测定、肺通气功能和小气道功能均与COPD患者的生命质量相关,深吸气量占预计值%和FEV_1占预计值%应联合作为临床评价COPD患者的客观指标. Objective To evaluate the correlation of the quality of life in patients with chronic obstructive pulmonary disease (COPD) with the lung function tests,especially the inspiratory capacity (IC).Methods Sixty-two stable COPD patients were enrolled between Jan.2006 and Mar.2007 (55 males and 7 females),with an age range of 43-79 (66±8) years.Lung volume,spirometry and small airway function measurements were performed in all patients.The St George respiratory questionnaire (SGRQ) score was collected.Pearson' s correlation coefficients were calculated.Results The total score of the 62 COPD patients was 43±17.The 3 component scores were:symptoms (54±23),activity (54±19) and impact (33±20).The FEV_1 pred% was (43±13)%,FEV_1/FVC was (52±11)%,residual volume (RV) pred% was (194±50)%,RV/total lung capacity (TLC) was (166±31)%,and IC pred% was (74±21)%.The SGRQ scores were significantly correlated with IC pred%,RV pred%,RV/TLC,FEV_1 pred%,FEV_1/FVC and small airway function measurements (FEF_(50%),FEF_(25%),MMEF).The correlation coefficients between the parameters of spirometry and the total score of SGRQ were-0.336 to-0.479,while those between the parameter of small airway function and the total score of SGRQ were-0.368 to -0.411.Among all these lung function measurements,ICpred% was best correlated with the SGRQ score,and the correlation coefficients between the IC pred% and the total score and the other 3 component scores of SGRQ were-0.418 to-0.521,respectively,P < 0.05.The symptoms section score had the poorest correlation with the lung function test.Conclusions The lung function test results correlate with the quality of life in patients with COPD.IC pred %,together with FEV_1 pred% should be used for clinical evaluation of patients with COPD.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/71187
Appears in Collections:北京大学第三临床医学院_呼吸内科_期刊论文

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作者单位: 北京大学第三医院呼吸科,100191

Recommended Citation:
沈宁,姚婉贞,刘政,等. 慢性阻塞性肺疾病患者深吸气量与生命质量的关系[J]. 中华结核和呼吸杂志,2010,33(4):261-264.
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