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IR@PKUHSC  > 北京大学第三临床医学院  > 呼吸内科  > 期刊论文
学科主题: 呼吸内科学
题名:
呼吸科和呼吸监护病房非发酵菌耐药性分析
其他题名: Antibiotic resistance of nonfermentative gram-negative bacilli in respiratory ward and respiratory intensive care unit
作者: 沈宁; 姚婉贞; 周庆涛; 陈亚红; 伍蕊; 刘振英
关键词: 呼吸科 ; 呼吸监护病房 ; 非发酵菌 ; 耐药性
刊名: 中国感染与化疗杂志
发表日期: 2007
DOI: 10.3321/j.issn:1009-7708.2007.03.013
卷: 7, 期:3, 页:202-205
收录类别: 中国科技核心期刊 ; 中文核心期刊
文章类型: Journal Article
摘要: 目的 研究我院呼吸科和呼吸监护病房(RICU)近5年呼吸道感染及耐药情况.方法 收集2001-2005年我院呼吸科和RICU分离出的呼吸道感染病原菌,对其中621株非发酵菌作体外药敏试验,对其结果进行分析比较.结果 5年中共分离出革兰阴性杆菌1 288株,其中呼吸科907株,RICU 381株.非发酵菌621株,占同期分离出的革兰阴性杆菌的48.3%.其中呼吸科306株,占革兰阴性杆菌的33.7%(306/907),铜绿假单胞菌最多见(146株,16.1%),其次为鲍曼不动杆菌(119株,13.1%),嗜麦芽窄食单胞菌(24株,2.6%)和其他(17株,1.9%).RICU 315株,占革兰阴性杆菌的82.7%(315/381),鲍曼不动杆菌最多见(134株,35.2%),其次为铜绿假单胞菌(113株,29.7%),嗜麦芽窄食单胞菌(50株,13.1%)和其他(18株,4.7%).铜绿假单胞菌对阿米卡星的敏感率最高,为81.3%,对亚胺培南的敏感率较低(48.8%);鲍曼不动杆菌对亚胺培南的敏感率最高,为95.6%,对头孢哌酮-舒巴坦的敏感率仅为40.4%;嗜麦芽窄食单胞菌对头孢哌酮-舒巴坦的敏感率最高,为86.8%,其次为左氧氟沙星(78.9%),头孢他啶(72.7%),对其他抗菌药的敏感率均很低.铜绿假单胞菌和鲍曼不动杆菌的耐药率在呼吸科和RICU有显著差异,而嗜麦芽窄食单胞菌的耐药率在2个病房差异不显著.结论 呼吸科中非发酵菌检出率高且耐药性强,在RICU分离菌株的耐药性明显高于普通病房,在应用抗菌药物治疗时应根据药敏结果和流行特点选择用药,避免进一步产生耐药菌.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/71241
Appears in Collections:北京大学第三临床医学院_呼吸内科_期刊论文

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作者单位: 1.北京大学第三医院呼吸科,北京,100083
2.北京大学第三医院检验科细菌室,北京,100083

Recommended Citation:
沈宁,姚婉贞,周庆涛,等. 呼吸科和呼吸监护病房非发酵菌耐药性分析[J]. 中国感染与化疗杂志,2007,7(3):202-205.
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