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学科主题: 呼吸内科学
题名:
老年慢性阻塞性肺疾病急性加重频率的影响因素
其他题名: Risk factors of acute exacerbation of COPD in elderly patients
作者: 张静; 陈亚红; 姚婉贞
关键词: 慢性阻塞性肺疾病 ; 急性加重频率 ; 肺功能 ; 生活质量 ; Chronic obstructive pulmonary disease ; Frequency of acute exacerbation ; Lung function ; Quality of life
刊名: 中国老年学杂志
发表日期: 2014
DOI: 10.3969/j.issn.1005-9202.2014.13.005
期: 13, 页:3526-3528
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的:探讨影响老年慢性阻塞性肺疾病( COPD)急性加重频率的因素。方法收集2010年10月至2011年6月北京大学第三医院门诊COPD稳定期患者临床资料,记录患者过去1年COPD急性加重次数、肺功能、生活质量( SGRQ)评分。根据患者过去1年COPD急性加重次数,将患者分为2组:非频发急性加重组为过去1年COPD急性加重次数≤2次,频发急性加重组为过去1年COPD急性加重次数>2次。结果频发急性加重组年龄比非频发急性加重组更大(P<0.01),但在性别、病程、吸烟史、吸烟包年无统计学差异。频发急性加重组患者吸入支气管扩张剂后FEV1%较非频发急性加重组患者降低(P<0.01)。其他肺功能指标差异无统计学意义(P>0.05);频发急性加重组患者 SGRQ活动评分较非频发急性加重组增加( P<0.05),而SGRQ症状评分、影响评分、总分两组之间差异无统计学意义( P<0.05)。结论高龄、肺功能差、生活质量活动评分增加是影响老年COPD患者急性加重频率的主要因素。 Objective To investigate the risk factors of acute exacerbation COPD in the elderly patients.Methods Outpatients with stable COPD from October 2011 to June 2011 in Peking University Third Hospital were enrolled.Times of exacerbation in last one year , lung function and SGRQ were assessed.Patients were divided into 2 groups with or without frequent exacerbation based on whether the exac-erbation times over twice or not.Results Patients with frequent exacerbation were elder ( P<0.01 ) , had higher SGRQ scores for activity (P<0.05) and lower FEV1% after bronchial dilator (P<0.01) than patients without frequent exacerbation.Conclusions Elder, lower FEV1%and increased SGRQ scores for activity are important risk factors for acute exacerbation COPD in elderly patients .
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/71248
Appears in Collections:北京大学第三临床医学院_呼吸内科_期刊论文

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作者单位: 北京大学第三医院呼吸科 北京 100191

Recommended Citation:
张静,陈亚红,姚婉贞. 老年慢性阻塞性肺疾病急性加重频率的影响因素[J]. 中国老年学杂志,2014(13):3526-3528.
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