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学科主题: 急诊医学
题名:
甲基强的松龙联合布地奈德雾化预防气管插管拔管后咽喉部不适的临床观察
其他题名: Clinical effect of methylprednisolone and budesonide suspension inhalation on relieving postextubation throat complications in patients undergoing tracheal intubation
作者: 刘慧琳; 李磊; 马青变
关键词: 糖皮质激素类 ; 插管法,气管内 ; Glucocorticoids ; Intubation,intratracheal
刊名: 中华老年医学杂志
发表日期: 2013
DOI: 10.3760/cma.j.issn.0254-9026.2013.10.008
卷: 32, 期:10, 页:1055-1057
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的 比较危重患者气管插管拔管前静脉使用甲基强的松龙和拔管前静脉使用甲基强的松龙联合拔管后即刻予以布地奈德雾化拔管后咽喉部不适症状的发生率. 方法 收集我院急诊重症监护病房2012年2月至2013年2月收治的75例气管插管患者,分为A组(拔管前静脉使用甲基强的松龙40 mg组)36例和B组(拔管前静脉使用甲基强的松龙40 mg联合拔管后即刻予以布地奈德1 mg雾化组)39例,观察两组患者拔管后咽喉部不适症状的发生情况,并进行疗效评价. 结果 A组咽痛发生率为50.0%(18/36)、声嘶为55.6%(20/36);B组咽痛发生率为30.8%(12/39)、声嘶为35.7%(14/39);喉头水肿发生率两组均不高,分别为2例(5.6 %)和1例(2.6%),虽差异均无统计学意义(x2=2.88、2.92、0.44,P=0.089、0.088、0.509),但B组发生率较A组呈下降趋势.结论气管插管拔管前使用甲基强的松龙且拔管后即刻予以布地奈德雾化吸入可能可减少拔管后患者咽痛、声嘶和喉头水肿的发生率. Objective To investigate the difference in the incidence of postextubation throat complications between severe patients treated with methylprednisolone intravenously with and without budesonide suspension inhalation immediately after postextubation.Methods 75 patients with tracheal intubation were divided into group A (n=36,patients received methylprednisolone 40 mg intravenously before extubation) and group B (n=39,patients received methylprednisolone 40 mg intravenously before extubation and budesonide suspension inhalation 1 mg immediately after extubation).Postextubation thoat complications including sore throat,hoarseness and laryngeal edema were observed in the two groups.Clinical efficacies in the two groups were analyzed.Results The incidences of sore throat,hoarseness and laryngeal edema after extubation were 50.0% (18/ 36),55.6% (20/36) and 5.6% (2/36) respectively in group A and 30.8% (12/39),35.7% (14/ 39) and 2.6% (1/39) respectively in group B.There were no significant differences in the incidences of sore throat,hoarseness and laryngeal edema after extubation between the two groups,but the tendencies of complication incidences were decreased in group B as compared with group A.Conclusions The application of intravenous methylprednisolone before extubation and budesonide suspension inhalation after extubation can reduce the incidences of sore throat,hoarseness and laryngeal edema after extubation.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/71415
Appears in Collections:北京大学第三临床医学院_急诊科_期刊论文

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作者单位: 1.100191,北京大学第三医院急诊科
2.100191,北京大学第三医院第二门诊部

Recommended Citation:
刘慧琳,李磊,马青变. 甲基强的松龙联合布地奈德雾化预防气管插管拔管后咽喉部不适的临床观察[J]. 中华老年医学杂志,2013,32(10):1055-1057.
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