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学科主题: 临床检验诊断学
题名:
自噬与缺血再灌注损伤
其他题名: Autophagy and ischemia/reperfusion injury
作者: 张文静; 崔丽艳; 张捷
关键词: 自噬 ; 缺血/再灌注损伤 ; Autophagy ; Ischemia/reperfusion injury
刊名: 检验医学
发表日期: 2014
DOI: 10.3969/j.issn.1673-8640.2014.02.022
期: 2, 页:182-185
收录类别: 中国科技核心期刊
文章类型: Journal Article
摘要: 自噬是存在于真核细胞生物中的一种细胞自我吞噬的现象。在生理状态下,可以维持机体内环境的稳定。在多种疾病的发生过程中,自噬也发挥重要作用。实验证明在缺血再灌注损伤的整个过程中,均有自噬的参与,但在缺血阶段和再灌注阶段,自噬有可能发挥不同的作用。在缺血阶段,自噬发挥保护细胞的作用,而在再灌注阶段,自噬可能会进一步加重细胞损伤甚至导致细胞死亡。 Autophagy is the phenomenon that cell phagocytose itself in eukaryotic organism.In physiological condition,autophagy can maintain the stability of environment in vivo.Autophagy plays an important role in the process of many diseases.Studies prove that autophagy participates in the process of ischemia/reperfusion injury.However,it may play different roles in the 2 processes.In the process of ischemia,autophagy can protect cells,while in the process of reperfusion,autophagy may aggravate cell injury and even lead to cell death.
语种: 中文
原文出处: 查看原文
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/71643
Appears in Collections:北京大学第三临床医学院_检验科_期刊论文

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作者单位: 北京大学第三医院检验科,北京,100191

Recommended Citation:
张文静,崔丽艳,张捷. 自噬与缺血再灌注损伤[J]. 检验医学,2014(2):182-185.
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