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学科主题: 麻醉学
题名:
围术期心肌缺血和心肌梗死研究进展
其他题名: Progress in perioperative myocardial ischaemia and myocardial infarction
作者: 贺端端; 吴长毅; 郭向阳
关键词: 围术期 ; 心肌缺血 ; 心肌梗死 ; 预防 ; Perioperative ; Myocardial ischaemia ; Myocardial infarction ; Prevention
刊名: 国际麻醉学与复苏杂志
发表日期: 2011
DOI: 10.3760/cma.j.issn.1673-4378.2011.04.025
卷: 32, 期:2, 页:225-228,235
收录类别: 中国科技核心期刊
文章类型: Journal Article
摘要: 背景 围术期多种因素可能导致心肌缺血和心肌梗死,了解其发生机制,有效预防,可降低围术期心脏事件发生率.目的 探讨围术期心肌缺血和心肌梗死的发生机制及有效预防措施.内窖冠状动脉粥样硬化后冠脉内皮对交感神经、副交感神经兴奋的反应性发生改变以及围术期特殊的病理生理状态是围术期心肌缺血和心肌梗死发生的主要机制.对于冠心病患者加强围术期心肌缺血和心肌梗死的监测与诊断,加强围术期药物治疗维持斑块稳定性、维持氧供需平衡,并完善术后镇痛、加强保温、避免血糖过高可减少围术期心肌缺血和心肌梗死的发生.趋向 冠心病患者非心脏手术前常规预防性药物的治疗时间与获益的关系以及术前冠脉重建的价值尚需进一步探讨. Background Many perioperative factors may result in myocardial ischaemia and myocardial infarction. Better understanding of the mechanism and effective prevention of it are all essential to decrease the incidence of perioperative cardiac event. Purpose To investigate the mechanism of perioperative myocardial ischaemia and myocardial infarction and their effective preventive measures. Content The change of the responsiveness of coronary atherosclerosis endodermis to sympathetic and parasympathetic stimulius along with the special pathophysiologic states may contribute to perioperative myocardial ischaemia and myocardial infarction. For patients with coronary artery disease, enhancing the monitor and diagnose of perioperative myocardial ischaemia and myocardial infarction, maintaining the stabilization of plaque and the banlance of myocardial oxygen supply and demand, improving postoperative analgesia, keeping normothermia and the avoidance of high blood glucose can decrease the incidence of perioperative myocardial infarction. Trend The relationship between the treatment duration of preoperative prophylactic drug therapy and the advantage as well as the value of preoperative coronary artery reconstitution for patients with coronary artery disease undergoing noncardiac operation still need to be researched.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/72209
Appears in Collections:北京大学第三临床医学院_麻醉科_期刊论文

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作者单位: 北京大学第三医院麻醉科,100191

Recommended Citation:
贺端端,吴长毅,郭向阳. 围术期心肌缺血和心肌梗死研究进展[J]. 国际麻醉学与复苏杂志,2011,32(2):225-228,235.
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