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学科主题: 泌尿外科学
题名:
肾移植后过客淋巴细胞综合征致重度溶血性贫血一例
其他题名: Severe hemolytic anemia caused by passenger lymphocyte syndrome after kidney transplantation: one case report
作者: 赵磊; 马潞林; 张洪宪; 侯小飞; 刘磊
关键词: 溶血性贫血 ; 过客淋巴细胞综合征 ; 肾移植 ; Hemolytic anemia ; Passenger lymphocyte syndrome ; Kidney transplantation
刊名: 中华器官移植杂志
发表日期: 2014
DOI: 10.3760/cma.j.issn.0254-1785.2014.11.008
卷: 35, 期:11, 页:672-675
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的 回顾1例肾移植术后由过客淋巴细胞综合征(PLS)导致的重度自身免疫性溶血性贫血(AIHA)的病例资料.方法 患者为男性,31岁,肾移植术后由于PLS继发AIHA发生严重贫血,直接抗球蛋白实验阳性、网织红细胞明显增高得以确诊.经输血、糖皮质激素、免疫球蛋白治疗后贫血明显改善,临床痊愈.结果 PLS是一个非常少见但是很重要的引起肾移植后AIHA的病因,常发生于A型受者接受O型供肾的情况下,确诊依靠溶血时在受者血清检出抗受者红细胞的抗体.结论 肾移植后出现不明原因贫血应考虑PLS引起AIHA的可能. Objective A kidney transplantation patient who was diagnosed with autoimmune hemolytic anemia (AIHA) caused by passenger lymphocyte syndrome (PLS) was reviewed.Method A male kidney transplantation patient aged 31 was admitted due to severe anemia.Direct antiglobulin test (DAT) was positive and reticulocyte was elevated significantly,and PLS was diagnosed.He was treated with blood transfusion,glucocorticoid and intravenous immunoglobulin,and recovered at last.Result PLS is a rare but important cause of AIHA after kidney transplantation,often occurs in blood type A patient who received a kidney from a blood type O donor.Final diagnosis depends on the detection of anti-erythrocyte antibody in recipient serum.Conclusion PLS should be considered when anemia with unknown reasons occurred in kidney transplantation patients.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/72415
Appears in Collections:北京大学第三临床医学院_泌尿外科_期刊论文

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作者单位: 100191,北京大学第三医院泌尿外科

Recommended Citation:
赵磊,马潞林,张洪宪,等. 肾移植后过客淋巴细胞综合征致重度溶血性贫血一例[J]. 中华器官移植杂志,2014,35(11):672-675.
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