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利拉鲁肽早期启用和长期治疗的可能获益
其他题名The possible benefits from early initiation and long-term treatment of liraglutide
洪天配
关键词利拉鲁肽 胰升糖素样肽1 糖尿病,2型 β细胞功能 Liraglutide Glucagon-like peptide-1 Diabetes mellitus,type 2 β cell function
刊名中华内分泌代谢杂志
2014
DOI10.3760/cma.j.issn.1000-6699.2014.12.023
30期:12页:1144-1147
收录类别中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型Journal Article
摘要胰岛β细胞功能减退是2型糖尿病的发生和发展的主要原因,早期纠正β细胞功能受损和遏制β细胞总量进行性下降是保证2型糖尿病患者血糖控制长期稳定的必要条件.基础和临床研究显示,长效胰升糖素样肽l类似物利拉鲁肽可保护β细胞功能和总量,早期启用对β细胞保护和血糖控制的效果更佳,长期治疗不仅可持续平稳控制血糖,还可持续减轻体重和减少内脏脂肪,并且具有潜在的心血管保护作用. Early intervention and preservation of β-cell function are essential for optimal glycemic control in the long term.Available data support the early use of the long-acting glucagon-like peptide-1 analogue liraglutide in preservation of β-cell mass and function,leading to better glycemic control.Besides glycemic control,persistent weight loss and reduced visceral adiposity are observed in type 2 diabetic patients treated with liraglutide,linking to its potential cardio-protective effects.
语种中文
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文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/72788
Collection北京大学第三临床医学院_内分泌科
作者单位100191,北京大学第三医院内分泌科
Recommended Citation
GB/T 7714
洪天配. 利拉鲁肽早期启用和长期治疗的可能获益[J]. 中华内分泌代谢杂志,2014,30(12):1144-1147.
APA 洪天配.(2014).利拉鲁肽早期启用和长期治疗的可能获益.中华内分泌代谢杂志,30(12),1144-1147.
MLA 洪天配."利拉鲁肽早期启用和长期治疗的可能获益".中华内分泌代谢杂志 30.12(2014):1144-1147.
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