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学科主题: 内分泌
题名:
亚临床甲状腺功能异常与心血管疾病的关系
其他题名: Relationship between subclinical thyroid dysfunction and cardiovascular disease
作者: 田勍; 刘国强; 洪天配
关键词: 亚临床甲状腺功能减退 ; 亚临床甲状腺功能亢进 ; 心血管疾病 ; Subclinical hypothyroidism ; Subclinical hyperthyroidism ; Cardiovascular disease
刊名: 国际内分泌代谢杂志
发表日期: 2010
DOI: 10.3760/cma.j.issn.1673-4157.2010.s1.006
卷: 30, 期:z1, 页:15-18
收录类别: 中国科技核心期刊 ; 中文核心期刊
文章类型: Journal Article
摘要: 临床研究显示,亚临床甲状腺功能异常与心血管疾病之间存在密切的关系.亚临床甲状腺功能减退通常伴有血脂异常、高凝状态、纤维蛋白溶解活性减低等心血管疾病危险因素,其与动脉粥样硬化、冠心病和心血管死亡的风险显著相关.另一方面,亚临床甲状腺功能亢进与心房颤动发生风险显著相关,但与心血管死亡风险的相关性尚不清楚.对于亚临床甲状腺功能异常进行治疗是否能够带来心血管获益,目前尚无确切结论. Clinical studies have shown a dose link between subclinical thyroid dysfunction and car-diovaseular disease. Subclinical hypothyroidism is associated with many cardiometabolic risk factors including dyslipidemia, hypercoagulabale state and decreased fibrinolytic activity ,and therefore contributes to increased risk for atherosclerosis,coronary artery disease and cardiovascular mortality. On the other hand, it has been reported that subclinical hyperthyroidism is associated with atrial fibrillation. However,the association of sub-clinical hyperthyroidism with cardiovascular mortality remains unclear. At present, there is no definite conclu-sion that the treatment of subclinical thyroid dysfunction can bring cardiovascular benefit.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/72873
Appears in Collections:北京大学第三临床医学院_内分泌科_期刊论文

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作者单位: 北京大学第三医院内分泌科,100191

Recommended Citation:
田勍,刘国强,洪天配. 亚临床甲状腺功能异常与心血管疾病的关系[J]. 国际内分泌代谢杂志,2010,30(z1):15-18.
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