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学科主题: 内分泌
题名:
转录因子Pax6在胰岛发育和糖代谢调节中的作用
其他题名: Role of transcription factor Pax6 in the development of pancreatic islets and the regulation of glucose metabolism
作者: 陈园园; 洪天配
关键词: 转录因子 ; Pax6 ; 糖代谢 ; 胰岛 ; 发育 ; Transcription factor ; Pax6 ; Glucose metabolism ; Islet ; Development
刊名: 国际内分泌代谢杂志
发表日期: 2009
DOI: 10.3760/cma.j.issn.1673-4157.2009.03.004
卷: 29, 期:3, 页:157-160
收录类别: 中国科技核心期刊 ; 中文核心期刊
文章类型: Journal Article
摘要: 配对盒因子6(Pax6)是一种重要的转录因子,在哺乳动物眼睛、中枢神经系统、胰岛等的发育中具有重要作用.业已证实,Pax6基因杂合子突变与糖代谢异常相关联.本文对Pax6基因在胰岛发育过程和血糖稳态调节中的作用进行讨论. Paired box 6(Pax6),a critical transcription factor,plays an important role in the development of eye,central nerve system and endocrine pancreas in mammals.It has been demonstrated that heterozygous mutation in Pax6 gene is associated with abnormal glucose metabolism.The role of Pax6 gene in the development of pancreatic islets as well as in the maintenance of glueose homeostasis is discussed in this article.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/72879
Appears in Collections:北京大学第三临床医学院_内分泌科_期刊论文

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作者单位: 北京大学第三医院内分泌科,100191

Recommended Citation:
陈园园,洪天配. 转录因子Pax6在胰岛发育和糖代谢调节中的作用[J]. 国际内分泌代谢杂志,2009,29(3):157-160.
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