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学科主题: 外科学
题名:
Dapper在肿瘤发病机制中的作用
其他题名: Role of Dapper in pathogenesis of cancer
作者: 王纪莲; 付卫
关键词: 肿瘤 ; 基因疗法 ; 基因,肿瘤抑制 ; 信号传导 ; Dapper ; Neoplasms ; Gene therapy ; Gene,turnor suppressor ; Signal transduction ; Dapper
刊名: 中华普外科手术学杂志(电子版)
发表日期: 2014
DOI: 10.3877/cma.j.issn.1674-3946.2014.02.052
期: 2, 页:175-177
文章类型: Journal Article
摘要: Dapper是作为Dishevelled的抑制因子而被新发现的,与信号转导通路,尤其是Wnt信号通路有着极其密切的关系,但是Dapper在Wnt信号通路的作用尚不明确。研究发现Dapper与肿瘤的发生发展有着极其重要的关系,通过研究Dapper在Wnt信号通路的作用及其作用机制,对于肿瘤的基因治疗有着极其重要的作用。 Dapper is newly found as an antagonist of the dishevelled , which has a close relationship with the Wnt signaling pathway .However , the exact function of Dapper in the Wnt signaling pathway is still obscure.Accumulated data showed that Dapper plays a critical role in tumorigenesis , and it is of great importance in gene therapy for cancer and to explore the function and molecular mechanisms of Dapper in the Wnt signaling pathway .
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/73189
Appears in Collections:北京大学第三临床医学院_普通外科_期刊论文

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作者单位: 100191,北京大学第三医院普通外科

Recommended Citation:
王纪莲,付卫. Dapper在肿瘤发病机制中的作用[J]. 中华普外科手术学杂志(电子版),2014(2):175-177.
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