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IR@PKUHSC  > 北京大学第三临床医学院  > 普通外科  > 期刊论文
学科主题: 外科学
题名:
sIL-2R和16在肝移植术后早期急性排斥和细菌感染中的诊断价值
其他题名: Significance of sIL-2R and IL-6 in the diagnosis of acute rejection and bacterial infection during liver transplantation
作者: 王港; 张同琳
关键词: 肝移植 ; 急性排斥 ; 细菌感染 ; 可溶性白细胞介素2受体 ; 白细胞介素6 ; Liver transplantation ; Acute rejection ; Bacterial infection ; Soluble interleukin - 2 receptor ; Interleukin - 6
刊名: 中国现代医学杂志
发表日期: 2004
DOI: 10.3969/j.issn.1005-8982.2004.02.007
卷: 14, 期:2, 页:28-32
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的探讨血浆和胆汁中可溶性白细胞介素2受体(sIL-2R)和白细胞介素6(IL-6)对于肝移植术后早期急性排斥和细菌感染的诊断价值.方法对20例肝移植患者进行研究,测定围手术期血浆及胆汁中的sIL-2R和IL-6.结果急性排斥时,血浆sIL-2R在病理诊断前就可升高,胆汁IL-6在4例患者中3例日升幅大于450 pg/ml;细菌感染时,血浆IL-6可明显升高;胆汁sIL-2R在急性排斥和细菌感染时均无明显变化.结论sIL-2R和IL-6对于肝移植术后早期急性排斥和细菌感染的诊断有一定的价值. Objective :To investigate the significance of soluble interleukin -2 receptor (sIL- 2R) and interleukin -6 (IL- 6) in plasma and bile in the diagnosis of acute rejection and bacterial infection in the early stage after liver transplantation. Methods: 20 patients undergoing orthotopic liver transplantation were included in our study.SIL- 2R and IL- 6 levels in plasma and bile were measured perioperatively by enzyme- linked immunoadsorbent assay. Results: Plasma sIL - 2R elevated prior to the pathological diagnosis of acute rejection and daily increase of IL6 in bile was more than 450 pg/ml ,which was seen in 3 of 4 patients prior to or at the onset of acute rejection. IL6 in plasma increased significantly when bacterial infection occurred, while slL- 2R in bile correlated with neither acute rejection nor bacterial infection. Conclusions: Measurements of sIL- 2R and IL- 6 may be useful in diagnosing acute rejection and bacterial injection during liver transplantation.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/73246
Appears in Collections:北京大学第三临床医学院_普通外科_期刊论文

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作者单位: 北京大学第三医院,普外科,北京,100083

Recommended Citation:
王港,张同琳. sIL-2R和16在肝移植术后早期急性排斥和细菌感染中的诊断价值[J]. 中国现代医学杂志,2004,14(2):28-32.
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