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学科主题: 临床医学
题名:
无创正压通气在急性加重期慢性阻塞性肺疾病合并重度二氧化碳潴留患者中的应用效果分析
其他题名: ANALYSIS ON THE APPLICATION VALUE OF NIPPV IN TREATMENT OF PATIENTS WITH AECOPD AND SEVERE CO2 RETENTION
作者: 赵茉
关键词: 慢性阻塞性肺疾病,急性加重期 ; 无创正压通气 ; 二氧化碳潴留 ; Chronic obstructive pulmonary diseases ; Acute exacerbation ; Noninvasive positive pressure ventilation ; Carbon dioxide retention
刊名: 中国煤炭工业医学杂志
发表日期: 2015
DOI: 10.11723/mtgyyx1007-9564201504008
期: 4, 页:542-544,545
收录类别: 中国科技核心期刊
文章类型: Journal Article
摘要: 目的:探讨无创正压通气(NIPPV)在急性加重期慢性阻塞性肺疾病(AECOPD)合并重度二氧化碳潴留患者中的应用效果。方法选择该院2010年4月—2014年9月收治的138例AECOPD合并重度二氧化碳潴留患者作为研究对象,在常规治疗的基础上采用 NIPPV治疗,分析治疗前后患者心率(HR)、呼吸(R)、氢离子浓度指数(PH)、血氧饱和度(SaO2)、氧分压(PaO2)和二氧化碳分压(PaCO2)改善情况。结果本次研究中气管插管率为20.42%(29/142),病死率为5.63%(8/142),NIPPV 有效率为79.58%(113/142)。HR和 R在治疗2h后虽有一定下降,但与治疗前比较差异无统计学意义(P>0.05)。治疗24h后 HR和 R均有较大幅度下降,与治疗前及治疗后2h 比较差异均有统计学意义(P<0.05)。SaO2、PH 和PaO2在治疗2h后及24h后增高均较为显著,而PaCO2在治疗2h后及24h后降低均较为显著,时点间比较差异均有统计学意义(P<0.05)。结论 NIPPV对合并重度二氧化碳潴留的 AECOPD患者有着良好的治疗效果,血气指标能够得到迅速改善。 Objective To evaluate the application value of NIPPV in treatment of patients with AECOPD and severe CO2 retention.Methods A total of 138 patients with AECOPD and severe CO2 retention from April 2010 to September 2014 in author's hospital were chosen as the experimental subjects,and were trea-ted with NIPPV on the basis of routine treatment,the HR,R,PH,SaO 2,PaO 2,PaCO2 were analyzed before and after treatment.Results In this study,the rate of endotracheal intubation was 20.42% (29/142),the mortality rate was 5.63% (8/142),the NIPPV efficiency was 79.58% (113/142).HR and R were decreased after 2h treatment,but no significant difference compared with before treatment (P>0.05).HR and R had significantly declined after 24h treatment,and had statistical significance compared with before and after 2h treatment (P<0.05).SaO2 ,PH and PaO2 were significantly increased after 2h and 24h treatment,but PaCO2 were significantly decreased after 2h and 24h treatment,timing differences were statistically significant (P<0.05).Conclusion NIPPV has good effects in patients with AECOPD and severe CO2 retention,blood gas indexes can be improved rapidly.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/75078
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: 北京大学第三医院海淀区院, 北京市,100089

Recommended Citation:
赵茉. 无创正压通气在急性加重期慢性阻塞性肺疾病合并重度二氧化碳潴留患者中的应用效果分析[J]. 中国煤炭工业医学杂志,2015(4):542-544,545.
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