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学科主题: 临床医学
题名:
胚胎干细胞向成骨、软骨细胞定向分化研究进展
其他题名: Progress in the study on osteogenic and chondrogenic differentiation of embryonic stem cells
作者: 柏海燕; 陈贵安
关键词: 胚胎干细胞 ; 分化 ; 软骨细胞 ; 成骨细胞 ; 组织工程 ; Embryonic stem cells ; Differentiation ; Chondrocytes ; Osteoblasts ; Tissue engineering
刊名: 国际生物医学工程杂志
发表日期: 2008
DOI: 10.3760/cma.j.issn.1673-4181.2008.06.014
卷: 31, 期:6, 页:375-379
收录类别: 中国科技核心期刊
文章类型: Journal Article
摘要: 骨、软骨组织工程的热点之一是寻找合适的种子细胞.胚胎干细胞因具有全能性和无限增殖的能力有望成为组织工程中的种子细胞新来源.主要介绍了胚胎干细胞定向诱导分化为成骨、软骨细胞研究所取得的进展,并展望了胚胎干细胞作为组织工程种子细胞的前景和所面临的困难. One of the focuses in bone and cartilage tissue engineering research is to find suitable seed cells. Embryonic stem cells derived from the inner cell mass of blastocysts possess unique characteristics such as unlimit- ed capacity of proliferation and the potential to differentiate into diverse cell types (pluripotentiality), which make them a promising cell source for tissue engineering. In this paper, the progress in the study on embryonic stem cell differentiating directly into osteoblasts and chondrocytes is introduced. The prospects and difficulties of using em- bryonic stem cells as seed cells for tissue engineering are also discussed.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/75130
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: 北京大学临床干细胞中心,北京大学第三医院妇产科生殖医学中心,100083

Recommended Citation:
柏海燕,陈贵安. 胚胎干细胞向成骨、软骨细胞定向分化研究进展[J]. 国际生物医学工程杂志,2008,31(6):375-379.
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