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B7-H6 as an efficient target for T cell-induced cytotoxicity in haematologic malignant cells 期刊论文
INVESTIGATIONAL NEW DRUGS, 2021, 卷号: 39, 期号: 1, 页码: 24-33
Authors:  Sun, Xin;  Zhao, Jingyuan;  Ma, Li;  Sun, Ximing;  Ge, Jing;  Yu, Yang;  Ma, Juan;  Zhang, Man
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B7-H6  FAMILY-MEMBER B7-H6  Bispecific antibody  BISPECIFIC ANTIBODIES  Haematologic malignancy  LIGAND  Immunotherapy  B7  NKP30  METASTASIS  MECHANISM  
Folic Acid/Peptides Modified PLGA-PEI-PEG Polymeric Vectors as Efficient Gene Delivery Vehicles: Synthesis, Characterization and Their Biological Performance 期刊论文
MOLECULAR BIOTECHNOLOGY, 2021, 卷号: 63, 期号: 1, 页码: 63-79
Authors:  Liu, Chaoyu;  Xie, Yuancai;  Li, Xiaohua;  Yao, Xumei;  Wang, Xuanbin;  Wang, Min;  Li, Zongxian;  Cao, Fengjun
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Polymeric vector  TRANSFECTION EFFICIENCY  Gene delivery  CO-DELIVERY  FOLIC acid  NANOPARTICLES  RGD peptide  MICELLES  Biocompatibility  CELL  Transfection efficiency  DNA  PEPTIDE  TRAFFICKING  COPOLYMERS  COMPLEXES  
Cytotoxicity Evaluation of Chloroquine and Hydroxychloroquine in Multiple Cell Lines and Tissues by Dynamic Imaging System and Physiologically Based Pharmacokinetic Model 期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: -
Authors:  Yang, Jianling;  Guo, Zhengyang;  Liu, Xu;  Liu, Qi;  Wu, Meng;  Yao, Xueting;  Liu, Yang;  Cui, Cheng;  Li, Haiyan;  Song, Chunli;  Liu, Dongyang;  Xue, Lixiang
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ratio of tissue trough concentrations  LUPUS-ERYTHEMATOSUS  dynamic imaging system  cytotoxicity  chloroquine and hydroxychloroquine  physiologically basedpharmacokinetic model  
UNG2 deacetylation confers cancer cell resistance to hydrogen peroxide-induced cytotoxicity 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 160, 页码: 403-417
Authors:  Bao, Yantao;  Tong, Lili;  Song, Boyan;  Liu, Ge;  Zhu, Qian;  Lu, Xiaopeng;  Zhang, Jun;  Lu, Ya-Fei;  Wen, He;  Tian, Yuan;  Sun, Yujie;  Zhu, Wei-Guo
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UNG2  URACIL-DNA GLYCOSYLASE  UHRF1  BASE EXCISION-REPAIR  ROS  PROTEASOMAL DEGRADATION  Oxidative DNA damage  HISTONE DEACETYLASES  HDAC inhibitor  N-GLYCOSYLASE  DAMAGE  UHRF1  TRANSCRIPTION  INHIBITION  EXPRESSION  
Hemolysin BL from novelBacillus toyonensisBV-17 induces antitumor activity both in vitro and in vivo 期刊论文
GUT MICROBES, 2020, 卷号: 12, 期号: 1, 页码: -
Authors:  Chen, Jiajia;  Hu, Shoukui;  Ji, Dengbo;  Gao, Zhaoya;  Wang, Hanyang;  Yang, Yong;  Chen, Yongkang;  Gu, Jin
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Gut microbiota  THERAPY  colorectal cancer  OBESITY  Bacillus toyonensisBV-17  hemolysinBL  antitumor activity  
Rhodamine B-based fluorescent probes for molecular mechanism study of the anti-influenza activity of pentacyclic triterpenes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 205, 期号: 0, 页码: 0
Authors:  Li, Man;  Yuan, Lan;  Chen, Yingying;  Ma, Wenxiao;  Ran, Fuxiang;  Zhang, Lihe;  Zhou, Demin;  Xiao, Sulong
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Pentacyclic triterpene  Rhodamine B  Fluorescent probe  Influenza virus  Subcellular localization  
Valproic acid enhances pamidronate-sensitized cytotoxicity of V delta 2(+) T cells against EBV-related lymphoproliferative cells 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2020, 卷号: 88, 页码: -
Authors:  Gao, Haitao;  Liu, Ruoyang;  Wu, Ning;  Mo, Xiao-Dong;  Han, Wei;  Huang, Xin;  Huang, Xiao-Jun;  Liu, Jiangying
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Bisphosphonates  BISPHOSPHONATES  Valproic acid  EXPRESSION  V delta 2(+) T cells  DISEASE  Epstein-Barrvirus  PTLD  
Photoswitchable CAR-T Cell Function In Vitro and In Vivo via a Cleavable Mediator 期刊论文
Cell Chemical Biology, 2020, 卷号: 28, 期号: 0, 页码: 1-10
Authors:  BoZhang;  YanWang;  ShenlongHuang;  JiaqiSun;  MinWang;  WenxiaoMa;  YanboYou;  LingWu;  JinHu;  WeiSong;  XudongLiu;  ShengjieLi;  HuaChen;  GuishengZhang;  LiheZhang;  DeminZhou;  LingjunLi;  XuanZhang
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CAR-T cytotoxicity  photoswitchable  cleavable mediator  fluorescein isothiocyanate  
Hydrogen Sulfide Protects Against Ammonia-Induced Neurotoxicity Through Activation of Nrf2/ARE Signaling in Astrocytic Model of Hepatic Encephalopathy 期刊论文
FRONTIERS IN CELLULAR NEUROSCIENCE, 2020, 卷号: 14, 页码: -
Authors:  Jin, Xiaozhi;  Chen, Dazhi;  Wu, Faling;  Zhang, Lei;  Huang, Yu;  Lin, Zhuo;  Wang, Xiaodong;  Wang, Rui;  Xu, Lanman;  Chen, Yongping
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hepatic encephalopathy  MITOCHONDRIAL PERMEABILITY TRANSITION  primary astrocytes  METHYLMERCURY-INDUCEDNEUROTOXICITY  H2S  OXIDATIVE STRESS  blood microbiota  INDUCED CYTOTOXICITY  Nrf2  CULTUREDASTROCYTES  REPERFUSION INJURY  INDUCED APOPTOSIS  BRAIN  PATHOGENESIS  ASSOCIATION  
TIGIT Can Exert Immunosuppressive Effects on CD8(+)T Cells by the CD155/TIGIT Signaling Pathway for Hepatocellular Carcinoma In Vitro 期刊论文
JOURNAL OF IMMUNOTHERAPY, 2020, 卷号: 43, 期号: 8, 页码: 236-243
Authors:  Zhang, Changkun;  Wang, Yang;  Xun, Xiaodong;  Wang, Siqi;  Xiang, Xiao;  Hu, Shihua;  Cheng, Qian;  Guo, Jinghang;  Li, Zhao;  Zhu, Jiye
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TIGIT  T-CELLS  HCC  KILLER-CELLS  CD8(+)T cell  EXPRESSION  immunosuppressive effect  OVEREXPRESSION  immunotherapy  ADHESION  DNAM-1  IMMUNOTHERAPY  CYTOTOXICITY  CD155  ACTIVATION