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Hydroxylated polychlorinated biphenyls (OH-PCBs) exert strong inhibitory effects towards human carboxylesterases (CESs) 期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 745, 页码: -
Authors:  Sun, Hong-Zhi;  Qin, Guo-Qiang;  Wang, Fei-Ge;  Bai, Yu;  Zhang, Zhipeng;  Fang, Zhong-Ze
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Polychlorinated biphenyls (PCBs)  UDP-GLUCURONOSYLTRANSFERASES UGTS  Toxicity mechanism  ESTROGENIC ACTIVITY  Carboxylesterases(CESs)  ARYLACETAMIDEDEACETYLASE  Enzyme inhibition  POTENT INHIBITION  In silico  METABOLITES  HYDROLYSIS  SULFOTRANSFERASE  INSIGHTS  PYRETHROIDS  ACTIVATION  
Triterpenoid-Mediated Inhibition of Virus–Host Interaction: Is Now the Time for Discovering Viral Entry/Release Inhibitors from Nature? 期刊论文
journal of medicinal chemistry, 2020, 期号: 0, 页码: 0
Authors:  Haiwei Li;  Jiaqi Sun;  Sulong Xiao;  Lihe Zhang;  Demin Zhou
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Infectious diseases  Hydrocarbons  Antimicrobial agents  Viruses  Inhibitors  
Low-dose L-NAME induces salt sensitivity associated with sustained increased blood volume and sodium-chloride cotransporter activity in rodents 期刊论文
KIDNEY INTERNATIONAL, 2020, 卷号: 98, 期号: 5, 页码: 1242-1252
Authors:  Wang, Conghui;  Kawakami-Mori, Fumiko;  Kang, Lei;  Ayuzawa, Nobuhiro;  Ogura, Sayoko;  Koid, Suang Suang;  Reheman, Latapati;  Yeerbolati, Alimila;  Liu, Beibei;  Yatomi, Yutaka;  Chen, Xiangmei;  Fujita, Toshiro;  Shimosawa, Tatsuo
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blood volume  ANGIOTENSIN-CONVERTING ENZYME  ENaC  NITRIC-OXIDE  L-NAME  RENAL VASODYSFUNCTION  natriuresis  VASCULAR DYSFUNCTION  NCC  L-ARGININE  nitric oxide  PRESSURE  oxidativestress  HYPERTENSION  sodium transporters  INHIBITION  salt sensitivity  NACL  SPAK  INITIATION  
Serum-deprivation leads to activation-like changes in primary microglia and BV-2 cells but not astrocytes 期刊论文
BIOMEDICAL REPORTS, 2020, 卷号: 13, 期号: 5, 页码: -
Authors:  Yao, Yao;  Fu, Kai-Yuan
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serum-deprivation  NITRIC-OXIDE SYNTHASE  microglia  PROTEIN-KINASE  lipopolysaccharide  LIPOPOLYSACCHARIDE  mitogen-activatedprotein kinase  EXPRESSION  activation-like changes  CULTURE  BRAIN  PAIN  INFLAMMATION  CONTRIBUTES  CYTOKINES  
Photoswitchable CAR-T Cell Function In Vitro and In Vivo via a Cleavable Mediator 期刊论文
Cell Chemical Biology, 2020, 卷号: 28, 期号: 0, 页码: 1-10
Authors:  BoZhang;  YanWang;  ShenlongHuang;  JiaqiSun;  MinWang;  WenxiaoMa;  YanboYou;  LingWu;  JinHu;  WeiSong;  XudongLiu;  ShengjieLi;  HuaChen;  GuishengZhang;  LiheZhang;  DeminZhou;  LingjunLi;  XuanZhang
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CAR-T cytotoxicity  photoswitchable  cleavable mediator  fluorescein isothiocyanate  
Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner 期刊论文
Redox Biology, 2020, 卷号: 37, 期号: -, 页码: -
Authors:  Yu Yan;  Xun Wu;  Pengcheng Wang;  Songyang Zhang;  Lulu Sun;  Yang Zhao;  GuangYi Zeng;  Bo Liu;  Guoheng Xu;  Huiying Liu;  Lei Wang;  Xian Wang;  ChangTao Jiang
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Hyperhomocysteinemia  Nonalcoholic fatty liver  Adipocyte lipolysis  ER oxidoreductin 1α  Hypoxia-inducible factor 1α  
Zbtb20 deficiency causes cardiac contractile dysfunction in mice 期刊论文
FASEB JOURNAL, 2020, 卷号: 34, 期号: 10, 页码: 13862-13876
Authors:  Ren, An-Jing;  Chen, Chao;  Zhang, Sha;  Liu, Mengna;  Wei, Chunchun;  Wang, Kai;  Ma, Xianhua;  Song, Yao;  Wang, Rui;  Zhang, Hai;  Chen, Yu-Xia;  Wu, Hong;  Xie, Zhifang;  Zhang, Youyi;  Zhang, Weiping J.
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blood pressure  FINGER PROTEIN ZBTB20  cardiomyocyte  BLOOD-PRESSURE  contractility  GENE  knockout  TRANSCRIPTION  mitochondrion  EXPRESSION  transcription factor  CA2+  DIFFERENTIATION  OVEREXPRESSION  MITOCHONDRIA  INDUCTION  
Anti-recoverin antibodies indicate fundus abnormalities in systemic lupus erythematosus 期刊论文
LUPUS, 2020, 卷号: 29, 期号: 11, 页码: 1346-1352
Authors:  Li, Min;  Cheng, Gong;  Wang, Zongyi;  Liu, Wen;  Jin, Yuebo;  Huang, Bo;  Wang, Yifan;  Qu, Jinfeng;  Shi, Guixiu;  Su, Yin;  He, Jing;  Li, Zhanguo
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Anti-recoverin antibodies  CANCER-ASSOCIATED RETINOPATHY  fundus abnormalities  AUTOIMMUNE RETINOPATHY  systemic lupuserythematosus  CELL-DEATH  AUTOANTIBODIES  PHOTORECEPTOR  APOPTOSIS  CALCIUM  DISEASE  INDUCE  
Increased SUMO-activating enzyme SAE1/UBA2 promotes glycolysis and pathogenic behavior of rheumatoid fibroblast-like synoviocytes 期刊论文
JCI INSIGHT, 2020, 卷号: 5, 期号: 18, 页码: -
Authors:  Wang, Cuicui;  Xiao, Youjun;  Lao, Minxi;  Wang, Jingnan;  Xu, Siqi;  Li, Ruiru;  Xu, Xuanxian;  Kuang, Yu;  Shi, Maohua;  Zou, Yaoyao;  Wang, Qingwen;  Liang, Liuqin;  Zheng, Song Guo;  Xu, Hanshi
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PYRUVATE-KINASE M2  NUCLEAR TRANSLOCATION  GENE-TRANSCRIPTION  PROTEIN  SUMOYLATION  PROLIFERATION  CLASSIFICATION  METABOLISM  EXPRESSION  MIGRATION  
Increased chemokine RANTES in synovial fluid and its role in early-stage degenerative temporomandibular joint disease 期刊论文
JOURNAL OF ORAL REHABILITATION, 2020, 卷号: 47, 期号: 9, 页码: 1150-1160
Authors:  Feng, Shi-Yang;  Lei, Jie;  Chen, Hui-Min;  Wang, Yi-Xiang;  Yap, Adrian U-Jin;  Fu, Kai-Yuan
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adolescent  TUMOR-NECROSIS-FACTOR  arthritis  KNEE OSTEOARTHRITIS  bone  DISC DISPLACEMENT  inflammatory processes  YOUNG-PATIENTS  inflammatorymarkers  DISORDERS  remodelling  PAIN  temporomandibular disorders  ADOLESCENTS  FEATURES