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Hydroxylated polychlorinated biphenyls (OH-PCBs) exert strong inhibitory effects towards human carboxylesterases (CESs)
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 745, 页码: -
Authors:
Sun, Hong-Zhi
;
Qin, Guo-Qiang
;
Wang, Fei-Ge
;
Bai, Yu
;
Zhang, Zhipeng
;
Fang, Zhong-Ze
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View/Download:1/0
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Submit date:2021/04/06
Polychlorinated biphenyls (PCBs)
UDP-GLUCURONOSYLTRANSFERASES UGTS
Toxicity mechanism
ESTROGENIC ACTIVITY
Carboxylesterases(CESs)
ARYLACETAMIDEDEACETYLASE
Enzyme inhibition
POTENT INHIBITION
In silico
METABOLITES
HYDROLYSIS
SULFOTRANSFERASE
INSIGHTS
PYRETHROIDS
ACTIVATION
Triterpenoid-Mediated Inhibition of Virus–Host Interaction: Is Now the Time for Discovering Viral Entry/Release Inhibitors from Nature?
期刊论文
journal of medicinal chemistry, 2020, 期号: 0, 页码: 0
Authors:
Haiwei Li
;
Jiaqi Sun
;
Sulong Xiao
;
Lihe Zhang
;
Demin Zhou
Adobe PDF(8351Kb)
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Submit date:2020/11/19
Infectious diseases
Hydrocarbons
Antimicrobial agents
Viruses
Inhibitors
Low-dose L-NAME induces salt sensitivity associated with sustained increased blood volume and sodium-chloride cotransporter activity in rodents
期刊论文
KIDNEY INTERNATIONAL, 2020, 卷号: 98, 期号: 5, 页码: 1242-1252
Authors:
Wang, Conghui
;
Kawakami-Mori, Fumiko
;
Kang, Lei
;
Ayuzawa, Nobuhiro
;
Ogura, Sayoko
;
Koid, Suang Suang
;
Reheman, Latapati
;
Yeerbolati, Alimila
;
Liu, Beibei
;
Yatomi, Yutaka
;
Chen, Xiangmei
;
Fujita, Toshiro
;
Shimosawa, Tatsuo
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Submit date:2021/03/09
blood volume
ANGIOTENSIN-CONVERTING ENZYME
ENaC
NITRIC-OXIDE
L-NAME
RENAL VASODYSFUNCTION
natriuresis
VASCULAR DYSFUNCTION
NCC
L-ARGININE
nitric oxide
PRESSURE
oxidativestress
HYPERTENSION
sodium transporters
INHIBITION
salt sensitivity
NACL
SPAK
INITIATION
Serum-deprivation leads to activation-like changes in primary microglia and BV-2 cells but not astrocytes
期刊论文
BIOMEDICAL REPORTS, 2020, 卷号: 13, 期号: 5, 页码: -
Authors:
Yao, Yao
;
Fu, Kai-Yuan
Adobe PDF(693Kb)
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View/Download:9/0
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Submit date:2021/03/09
serum-deprivation
NITRIC-OXIDE SYNTHASE
microglia
PROTEIN-KINASE
lipopolysaccharide
LIPOPOLYSACCHARIDE
mitogen-activatedprotein kinase
EXPRESSION
activation-like changes
CULTURE
BRAIN
PAIN
INFLAMMATION
CONTRIBUTES
CYTOKINES
Photoswitchable CAR-T Cell Function In Vitro and In Vivo via a Cleavable Mediator
期刊论文
Cell Chemical Biology, 2020, 卷号: 28, 期号: 0, 页码: 1-10
Authors:
BoZhang
;
YanWang
;
ShenlongHuang
;
JiaqiSun
;
MinWang
;
WenxiaoMa
;
YanboYou
;
LingWu
;
JinHu
;
WeiSong
;
XudongLiu
;
ShengjieLi
;
HuaChen
;
GuishengZhang
;
LiheZhang
;
DeminZhou
;
LingjunLi
;
XuanZhang
Adobe PDF(3315Kb)
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View/Download:9/0
  |  
Submit date:2020/11/19
CAR-T cytotoxicity
photoswitchable
cleavable mediator
fluorescein isothiocyanate
Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner
期刊论文
Redox Biology, 2020, 卷号: 37, 期号: -, 页码: -
Authors:
Yu Yan
;
Xun Wu
;
Pengcheng Wang
;
Songyang Zhang
;
Lulu Sun
;
Yang Zhao
;
GuangYi Zeng
;
Bo Liu
;
Guoheng Xu
;
Huiying Liu
;
Lei Wang
;
Xian Wang
;
ChangTao Jiang
Adobe PDF(10232Kb)
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Submit date:2020/12/16
Hyperhomocysteinemia
Nonalcoholic fatty liver
Adipocyte lipolysis
ER oxidoreductin 1α
Hypoxia-inducible factor 1α
Zbtb20 deficiency causes cardiac contractile dysfunction in mice
期刊论文
FASEB JOURNAL, 2020, 卷号: 34, 期号: 10, 页码: 13862-13876
Authors:
Ren, An-Jing
;
Chen, Chao
;
Zhang, Sha
;
Liu, Mengna
;
Wei, Chunchun
;
Wang, Kai
;
Ma, Xianhua
;
Song, Yao
;
Wang, Rui
;
Zhang, Hai
;
Chen, Yu-Xia
;
Wu, Hong
;
Xie, Zhifang
;
Zhang, Youyi
;
Zhang, Weiping J.
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Submit date:2021/03/09
blood pressure
FINGER PROTEIN ZBTB20
cardiomyocyte
BLOOD-PRESSURE
contractility
GENE
knockout
TRANSCRIPTION
mitochondrion
EXPRESSION
transcription factor
CA2+
DIFFERENTIATION
OVEREXPRESSION
MITOCHONDRIA
INDUCTION
Anti-recoverin antibodies indicate fundus abnormalities in systemic lupus erythematosus
期刊论文
LUPUS, 2020, 卷号: 29, 期号: 11, 页码: 1346-1352
Authors:
Li, Min
;
Cheng, Gong
;
Wang, Zongyi
;
Liu, Wen
;
Jin, Yuebo
;
Huang, Bo
;
Wang, Yifan
;
Qu, Jinfeng
;
Shi, Guixiu
;
Su, Yin
;
He, Jing
;
Li, Zhanguo
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Submit date:2021/03/09
Anti-recoverin antibodies
CANCER-ASSOCIATED RETINOPATHY
fundus abnormalities
AUTOIMMUNE RETINOPATHY
systemic lupuserythematosus
CELL-DEATH
AUTOANTIBODIES
PHOTORECEPTOR
APOPTOSIS
CALCIUM
DISEASE
INDUCE
Increased SUMO-activating enzyme SAE1/UBA2 promotes glycolysis and pathogenic behavior of rheumatoid fibroblast-like synoviocytes
期刊论文
JCI INSIGHT, 2020, 卷号: 5, 期号: 18, 页码: -
Authors:
Wang, Cuicui
;
Xiao, Youjun
;
Lao, Minxi
;
Wang, Jingnan
;
Xu, Siqi
;
Li, Ruiru
;
Xu, Xuanxian
;
Kuang, Yu
;
Shi, Maohua
;
Zou, Yaoyao
;
Wang, Qingwen
;
Liang, Liuqin
;
Zheng, Song Guo
;
Xu, Hanshi
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  |  
Submit date:2021/04/06
PYRUVATE-KINASE M2
NUCLEAR TRANSLOCATION
GENE-TRANSCRIPTION
PROTEIN
SUMOYLATION
PROLIFERATION
CLASSIFICATION
METABOLISM
EXPRESSION
MIGRATION
Increased chemokine RANTES in synovial fluid and its role in early-stage degenerative temporomandibular joint disease
期刊论文
JOURNAL OF ORAL REHABILITATION, 2020, 卷号: 47, 期号: 9, 页码: 1150-1160
Authors:
Feng, Shi-Yang
;
Lei, Jie
;
Chen, Hui-Min
;
Wang, Yi-Xiang
;
Yap, Adrian U-Jin
;
Fu, Kai-Yuan
Adobe PDF(1615Kb)
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  |  
View/Download:6/0
  |  
Submit date:2021/03/09
adolescent
TUMOR-NECROSIS-FACTOR
arthritis
KNEE OSTEOARTHRITIS
bone
DISC DISPLACEMENT
inflammatory processes
YOUNG-PATIENTS
inflammatorymarkers
DISORDERS
remodelling
PAIN
temporomandibular disorders
ADOLESCENTS
FEATURES