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Germline variants of DNA repair genes in early onset mantle cell lymphoma 期刊论文
ONCOGENE, 2021, 卷号: 40, 期号: 3, 页码: 551-563
Authors:  Wang, Xiaogan;  Song, Yuqin;  Chen, Wei;  Ding, Ning;  Liu, Weiping;  Xie, Yan;  Wang, Yinan;  Zhu, Jun;  Zeng, Changqing
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NON-HODGKINS-LYMPHOMA  MICROSATELLITE INSTABILITY  MOLECULARPATHOGENESIS  CANCER  EXPRESSION  ASSOCIATION  DEFICIENCY  SIGNATURES  ALIGNMENT  PATIENT  
ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway 期刊论文
DIABETES, 2021, 卷号: 70, 期号: 1, 页码: 214-226
Authors:  Mao, Zhuo;  Feng, Mingji;  Li, Zhuoran;  Zhou, Minsi;  Xu, Langning;  Pan, Ke;  Wang, Shaoxiang;  Su, Wen;  Zhang, Weizhen
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TRANSCRIPTION FACTORS  GROWTH  LOCI  
New insights on brain-derived neurotrophic factor epigenetics: from depression to memory extinction 期刊论文
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 2021, 卷号: 1484, 期号: 1, 页码: 9-31
Authors:  Poon, Chi Him;  Heng, Boon Chin;  Lim, Lee Wei
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depression  BDNF PROMOTER METHYLATION  brain-derived neurotrophic factor  HIPPOCAMPAL CELL-PROLIFERATION  DNA methylation  FAMILYTRANSCRIPTION FACTOR  histonemodification  DNA METHYLATION  memory extinction  FEAR EXTINCTION  PREFRONTALCORTEX  INFRALIMBIC CORTEX  MAJOR DEPRESSION  PRENATAL STRESS  GENE-EXPRESSION  
Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors 期刊论文
NATURE GENETICS, 2020, 卷号: 52, 期号: 12, 页码: 1303-1313
Authors:  Bakker, Mark K.;  van der Spek, Rick A. A.;  van Rheenen, Wouter;  Morel, Sandrine;  Bourcier, Romain;  Hostettler, Isabel C.;  Alg, Varinder S.;  van Eijk, Kristel R.;  Koido, Masaru;  Akiyama, Masato;  Terao, Chikashi;  Matsuda, Koichi;  Walters, Robin G.;  Lin, Kuang;  Li, Liming;  Millwood, Iona Y.;  Chen, Zhengming;  Rouleau, Guy A.;  Zhou, Sirui;  Rannikmae, Kristiina;  Sudlow, Cathie L. M.;  Houlden, Henry;  van den Berg, Leonard H.;  Dina, Christian;  Naggara, Olivier;  Gentric, Jean-Christophe;  Shotar, Eimad;  Eugene, Francois;  Desal, Hubert;  Winsvold, Bendik S.;  Borte, Sigrid;  Johnsen, Marianne Bakke;  Brumpton, Ben M.;  Sandvei, Marie Softeland;  Willer, Cristen J.;  Hveem, Kristian;  Zwart, John-Anker;  Verschuren, W. M. Monique;  Friedrich, Christoph M.;  Hirsch, Sven;  Schilling, Sabine;  Dauvillier, Jerome;  Martin, Olivier;  Winsvold, Bendik S.;  Winsvold, Bendik S.;  Borte, Sigrid;  Johnsen, Marianne Bakke;  Brumpton, Ben M.;  Sandvei, Marie Softeland;  Willer, Cristen J.;  Hveem, Kristian;  Zwart, John-Anker;  Bian, Zheng;  Chen, Junshi;  Chen, Yiping;  Chen, Zhengming;  Clarke, Robert;  Collins, Rory;  Guo, Yu;  Han, Xiao;  Hill, Michael;  Li, Liming;  Lin, Kuang;  Liu, Depei;  Lv, Jun;  Millwood, Iona;  Peto, Richard;  Sansome, Sam;  Walters, Robin;  Yang, Xiaoming;  Yu, Canqing;  Koido, Masaru;  Koido, Masaru;  Akiyama, Masato;  Terao, Chikashi;  Matsuda, Koichi;  Kamatani, Yoichiro;  Desal, Hubert;  Desal, Hubert;  Bourcier, Romain;  Redon, Richard;  Dina, Christian;  Naggara, Olivier;  Eugene, Francois;  Gentric, Jean-Christophe;  Shotar, Eimad;  Sargurupremraj, Muralidharan;  Tatlisumak, Turgut;  Debette, Stephanie;  Werring, David J.;  Houlden, Henry;  Alg, Varinder S.;  Hostettler, Isabel C.;  Bonner, Stephen;  Walsh, Daniel;  Bulters, Diederik;  Kitchen, Neil;  Brown, Martin;  Grieve, Joan;  Bakker, Mark K.;  Bourcier, Romain;  Walters, Robin G.;  Malik, Rainer;  Dichgans, Martin;  Sargurupremraj, Muralidharan;  Tatlisumak, Turgut;  Debette, Stephanie;  Rinkel, Gabriel J. E.;  Worrall, Bradford B.;  Pera, Joanna;  Slowik, Agnieszka;  Broderick, Joseph P.;  Werring, David J.;  Woo, Daniel;  Bijlenga, Philippe;  Kamatani, Yoichiro;  Ruigrok, Ynte M.;  Jones, Gregory T.;  Bown, Matthew J.;  Ko, Nerissa U.;  Kim, Helen;  Coleman, Jonathan R. I.;  Breen, Gerome;  Zaroff, Jonathan G.;  Klijn, Catharina J. M.;  Malik, Rainer;  Dichgans, Martin;  Sargurupremraj, Muralidharan;  Tatlisumak, Turgut;  Amouyel, Philippe;  Debette, Stephanie;  Rinkel, Gabriel J. E.;  Worrall, Bradford B.;  Pera, Joanna;  Slowik, Agnieszka;  Gaal-Paavola, Emilia I.;  Niemela, Mika;  Jaaskelainen, Juha E.;  von Und Zu Fraunberg, Mikael;  Lindgren, Antti;  Broderick, Joseph P.;  Werring, David J.;  Woo, Daniel;  Redon, Richard;  Bijlenga, Philippe;  Kamatani, Yoichiro;  Veldink, Jan H.;  Ruigrok, Ynte M.
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LD SCORE REGRESSION  SUBARACHNOID HEMORRHAGE  GWAS  METAANALYSIS  SEX  HERITABILITY  VARIANTS  SMOKING  PATIENT  GROWTH  
Genome-Wide Meta-Analysis Identifies Three Novel Susceptibility Loci and Reveals Ethnic Heterogeneity of Genetic Susceptibility for IgA Nephropathy 期刊论文
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2020, 卷号: 31, 期号: 12, 页码: 2949-2963
Authors:  Li, Ming;  Wang, Ling;  Shi, Dian-Chun;  Foo, Jia-Nee;  Zhong, Zhong;  Khor, Chiea-Chuen;  Lanzani, Chiara;  Citterio, Lorena;  Salvi, Erika;  Yin, Pei-Ran;  Bei, Jin-Xin;  Wang, Li;  Liao, Yun-Hua;  Chen, Jian;  Chen, Qin-Kai;  Xu, Gang;  Jiang, Geng-Ru;  Wan, Jian-Xin;  Chen, Meng-Hua;  Chen, Nan;  Zhang, Hong;  Zeng, Yi-Xin;  Liu, Zhi-Hong;  Liu, Jian-Jun;  Yu, Xue-Qing
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IgA nephropathy  PRIMARY GLOMERULAR-DISEASES  meta-analysis  EPIDEMIOLOGIC DATA  genome-wide association study  CHANGING SPECTRUM  commonvariants  ASSOCIATION  PROTEIN  VARIANT  FAMILY  FCRL3  IRF4  HLA  
GJA1 Gene Polymorphisms and Topographic Distribution of Cranial MRI Lesions in Cerebral Small Vessel Disease 期刊论文
FRONTIERS IN NEUROLOGY, 2020, 卷号: 11, 页码: -
Authors:  Zhang, Jing;  You, Qian;  Shu, Junlong;  Gang, Qiang;  Jin, Haiqiang;  Yu, Meng;  Sun, Wei;  Zhang, Wei;  Huang, Yining
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CSVD  BLOOD-BRAIN-BARRIER  distribution  RATING-SCALE  MRI  HAN CHINESE  connexins  ASSOCIATION  gene polymorphism  RISK  HEMICHANNELS  CONNEXINS  CYTOKINES  TRANSPORT  CHANNELS  
Bidirectional Causal Associations Between Inflammatory Bowel Disease and Ankylosing Spondylitis: A Two-Sample Mendelian Randomization Analysis 期刊论文
FRONTIERS IN GENETICS, 2020, 卷号: 11, 页码: -
Authors:  Cui, Zhiyong;  Hou, Guojin;  Meng, Xiangyu;  Feng, Hui;  He, Baichuan;  Tian, Yun
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ankylosing spondylitis  CARD15 GENE POLYMORPHISMS  inflammatory bowel disease  AXIAL SPONDYLOARTHRITIS  ulcerative colitis  DIAGNOSTIC-CRITERIA  Crohn’  SUSCEPTIBILITY LOCI  s disease  RISK  Mendelian randomization  MANIFESTATIONS  IDENTIFICATION  CLASSIFICATION  EPIDEMIOLOGY  IDENTIFY  
Associations between gut microbiota and Alzheimers disease, major depressive disorder, and schizophrenia 期刊论文
JOURNAL OF NEUROINFLAMMATION, 2020, 卷号: 17, 期号: 1, 页码: -
Authors:  Zhuang, Zhenhuang;  Yang, Ruotong;  Wang, Wenxiu;  Qi, Lu;  Huang, Tao
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Gut microbiota  GENOME-WIDE ASSOCIATION  Neuropsychiatric disorder  PLATELET SEROTONIN  Mendelian randomization  MOUSE MODEL  Genetic association  BRAIN  Causality  METAANALYSIS  DYSBIOSIS  SYMPTOMS  ACIDS  LOCI  
Differences in clinical and genetic characteristics between early- and late-onset narcolepsy in a Han Chinese cohort 期刊论文
NEURAL REGENERATION RESEARCH, 2020, 卷号: 15, 期号: 10, 页码: 1887-+
Authors:  Ouyang, Hui;  Han, Fang;  Zhou, Ze-Chen;  Zhang, Jun
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case-control studies  clinical features  genetic association studies  genetic load  genetic loci  genetic phenomena  hypothalamic diseases  precision medicine  risk assessment  single nucleotide polymorphism  
Identification of genetic loci jointly influencing coronary artery disease risk and sleep traits of insomnia, sleep duration, and chronotype 期刊论文
SLEEP MEDICINE, 2020, 卷号: 74, 页码: 116-123
Authors:  Zheng, Qiwen;  Ma, Yujia;  Chen, Si;  Che, Qianzi;  Zhou, Zechen;  Chen, Dafang
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Coronary artery disease  GENOME-WIDE ASSOCIATION  Sleep  HEALTH OUTCOMES  Genetic pleiotropy  METAANALYSIS  Genome-wideassociation study  ARCHITECTURE  EXPRESSION  PLASTICITY  PATHWAYS  MEMORY