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Clinical Translation of a Ga-68-Labeled Integrin alpha(v)beta(6)-Targeting Cyclic Radiotracer for PET Imaging of Pancreatic Cancer 期刊论文
JOURNAL OF NUCLEAR MEDICINE, 2020, 卷号: 61, 期号: 10, 页码: 1461-1467
Authors:  Feng, Xun;  Wang, Yanpu;  Lu, Dehua;  Xu, Xiaoxia;  Zhou, Xin;  Zhang, Huiyuan;  Zhang, Ting;  Zhu, Hua;  Yang, Zhi;  Wang, Fan;  Lie, Nan;  Liu, Zhaofei
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pancreatic cancer  POSITRON-EMISSION-TOMOGRAPHY  integrin alpha(v)beta(6)  CYSTINE KNOT PEPTIDES  Ga-68 radiotracer  ALPHA-V-BETA-6INTEGRIN  PET/CT  PHOTODYNAMIC THERAPY  cycratide  EXPRESSION  
Fibrinogen alpha chain promotes the migration and invasion of human endometrial stromal cells in endometriosis through focal adhesion kinase/protein kinase B/matrix metallopeptidase 2 pathway 期刊论文
BIOLOGY OF REPRODUCTION, 2020, 卷号: 103, 期号: 4, 页码: 779-790
Authors:  Li, Hui;  Ma, Rui-Qiong;  Cheng, Hong-Yan;  Ye, Xue;  Zhu, Hong-Lan;  Chang, Xiao-Hong
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endometriosis  EUTOPIC ENDOMETRIUM  fibrinogen alpha chain  FGA  migration  BIOMARKERS  invasion  INTEGRIN  FAK/AKTpathway  IDENTIFICATION  ESTABLISHMENT  PATHOGENESIS  METASTASIS  EXPRESSION  PEPTIDES  
Design of integrin alpha(v)beta(3) targeting self-assembled protein nanoparticles with RGD peptide 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2020, 卷号: 128, 页码: -
Authors:  Lv, Xiangfeng;  Zhang, Chun;  Shuaizhen, Qingyun;  Yu, Rong;  Zheng, Yongxiang
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RGD  TUMOR  BAK  ALPHA-V-BETA-3  Self-assembled protein nanoparticles  DELIVERY  Integrinalpha(v)beta(3)  BINDING  Tumor targeting  BAK  Pro-apoptosis  
Role of YAP/TAZ in Cell Lineage Fate Determination and Related Signaling Pathways 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 卷号: 8, 期号: 0, 页码: 735
Authors:  Heng, Boon C.;  Zhang, Xuehui;  Aubel, Dominique;  Bai, Yunyang;  Li, Xiaochan;  Wei, Yan;  Fussenegger, Martin;  Deng, Xuliang
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differentiation  MESENCHYMAL STEM-CELLS  Hippo  YES-ASSOCIATED PROTEIN  signaling  STIMULATES OSTEOGENICDIFFERENTIATION  stem cells  PROMOTE KERATINOCYTE PROLIFERATION  TAZ  REGULATES EMBRYONICNEUROGENESIS  YAP  AMPK-MEDIATED REGULATION  RAT BONE-MARROW  HIPPO PATHWAY  ADIPOGENIC DIFFERENTIATION  TUMOR-SUPPRESSOR  
LOX-1 RegulatesP. gingivalis-Induced Monocyte Migration and Adhesion to Human Umbilical Vein Endothelial Cells 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 卷号: 8, 期号: 0, 页码: -0
Authors:  Li, Qian;  Liu, Jianru;  Liu, Wenyi;  Chu, Yi;  Zhong, Jinsheng;  Xie, Ying;  Lou, Xinzhe;  Ouyang, Xiangying
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Porphyromonas gingivalis  LOW-DENSITY-LIPOPROTEIN  LOX-1  NF-KAPPA-B  THP-1 cells  PORPHYROMONAS-GINGIVALIS  HUVECs  EXPRESSION  migration  RECEPTOR  adhesion  IDENTIFICATION  INFLAMMATION  MODULATION  DISEASE  
A Cu-64-porphyrin-based dual-modal molecular probe with integrin alpha(v)beta(3) targeting function for tumour imaging 期刊论文
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2020, 卷号: 63, 期号: 5, 页码: 212-221
Authors:  Ai, Lin;  Shi, Jiyun;  Fan, Di;  Wang, Kai;  Gao, Hannan;  Luo, Qi;  Wang, Xin;  Li, Xiaotong;  Tong, Wu;  Zhang, Xin;  Luo, Chuangwei;  Yang, Guangjie
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integrin alpha(v)beta(3)  molecular probe  optical imaging  PET imaging  pyropheophorbide-a  
An Integrin Alpha 6-Targeted Radiotracer with Improved Receptor Binding Affinity and Tumor Uptake 期刊论文
BIOCONJUGATE CHEMISTRY, 2020, 卷号: 31, 期号: 5, 页码: 1510-1521
Authors:  Luo, Qi;  Yang, Guangjie;  Gao, Hannan;  Wang, Yanpu;  Luo, Chuangwei;  Ma, Xiaotu;  Gao, Yu;  Li, Xiaoda;  Zhao, Huiyun;  Jia, Bing;  Shi, Jiyun;  Wang, Fan
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HEPATOCELLULAR-CARCINOMA  RGD DIMERS  ANGIOGENESIS  DOSIMETRY  CANCER  
LXW7 attenuates inflammation via suppressing Akt/nuclear factor kappa B and mitogen-activated protein kinases signaling pathways in lipopolysaccharide-stimulated BV2 microglial cells 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2019, 卷号: 77
Authors:  Peng, Sijia;  Jia, Jingjing;  Sun, Jingjing;  Xie, Qizhi;  Zhang, Xiaoyun;  Deng, Yuanfei;  Yi, Li
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Integrin inhibitor  NITRIC-OXIDE  LXW7  RESPONSES  Inflammation  MAPK  Microglia  NEURODEGENERATION  Akt/NF-kappa B  INHIBITION  MAPK  MECHANISMS  DISEASES  PEPTIDE  MODEL  ACID  
Construction of a Targeting Nanoparticle of 3 ′,3 ′′-Bis-Peptide-siRNA Conjugate/Mixed Lipid with Postinserted DSPE-PEG2000-cRGD 期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 12, 页码: 4920-4928
Authors:  Zhang, Yanfen;  Li, Sixiu;  Zhou, Xinyang;  Sun, Jing;  Fan, Xinmeng;  Guan, Zhu;  Zhang, Lihe;  Yang, Zhenjun
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bis-peptide-siRNA  IN-VITRO  CLD  SYSTEMIC DELIVERY  DNCA  SIRNA DELIVERY  cRGD  RGD PEPTIDE  uptake pathways  LIPOSOMES  CRGD  OPTIMIZATION  THERAPY  
CeO2@PAA-LXW7 Attenuates LPS-Induced Inflammation in BV2 Microglia 期刊论文
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2019, 卷号: 39, 期号: 8, 页码: 1125-1137
Authors:  Jia, Jingjing;  Li, Changyan;  Zhang, Ting;  Sun, Jingjing;  Peng, Sijia;  Xie, Qizhi;  Huang, Yining;  Yi, Li
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Cerium Nanoparticles  Cerium Oxide Nanoparticles  Lxw7  Focal Cerebral-ischemia  Integrin Alpha v Beta 3  Synaptic Plasticity  Inflammation  Endothelial-cells  Oxidative Stress  Signal Transducer  Adhesion Kinase  Integrin  Expression  Peptide  Brain