北京大学医学部机构知识库(IR@PKUHSC): Search Results

Genome-Wide Meta-Analysis Identifies Three Novel Susceptibility Loci and Reveals Ethnic Heterogeneity of Genetic Susceptibility for IgA Nephropathy 期刊论文
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2020, 卷号: 31, 期号: 12, 页码: 2949-2963
Authors: Li, Ming; Wang, Ling; Shi, Dian-Chun; Foo, Jia-Nee; Zhong, Zhong; Khor, Chiea-Chuen; Lanzani, Chiara; Citterio, Lorena; Salvi, Erika; Yin, Pei-Ran; Bei, Jin-Xin; Wang, Li; Liao, Yun-Hua; Chen, Jian; Chen, Qin-Kai; Xu, Gang; Jiang, Geng-Ru; Wan, Jian-Xin; Chen, Meng-Hua; Chen, Nan; Zhang, Hong; Zeng, Yi-Xin; Liu, Zhi-Hong; Liu, Jian-Jun; Yu, Xue-Qing

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IgA nephropathy PRIMARY GLOMERULAR-DISEASES meta-analysis EPIDEMIOLOGIC DATA genome-wide association study CHANGING SPECTRUM commonvariants ASSOCIATION PROTEIN VARIANT FAMILY FCRL3 IRF4 HLA

Genetic risk, adherence to a healthy lifestyle, and type 2 diabetes risk among 550,000 Chinese adults: results from 2 independent Asian cohorts 期刊论文
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2020, 卷号: 111, 期号: 3, 页码: 698-707
Authors: Li, Haoxin; Khor, Chiea-Chuen; Fan, Junning; Lv, Jun; Yu, Canqing; Guo, Yu; Bian, Zheng; Yang, Ling; Millwood, Iona Y.; Walters, Robin G.; Chen, Yiping; Yuan, Jian-Min; Yang, Yan; Hu, Chen; Chen, Junshi; Chen, Zhengming; Koh, Woon-Puay; Huang, Tao; Li, Liming

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type 2 diabetes BODY-MASS INDEX genetics MENDELIAN RANDOMIZATION gene-environment interaction PREVALENCE Chinese VARIANTS lifestyle SMOKING PATTERN TRAITS WOMEN MEN

Associations of autozygosity with a broad range of human phenotypes 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10
Authors: Wareham, Nicholas J.; Wild, Sarah; Yajnik, Chittaranjan S.; Yuan, Jian-Min; Zeng, Lingyao; Zhang, Liang; Zhou, Jie; Amin, Najaf; Asselbergs, Folkert W.; Bakker, Stephan J. L.; Becker, Diane M.; Lehne, Benjamin; Bennett, David A.; van den Berg, Leonard H.; Berndt, Sonja I.; Bharadwaj, Dwaipayan; Bielak, Lawrence F.; Bochud, Murielle; Boehnke, Mike; Bouchard, Claude; Bradfield, Jonathan P.; Brody, Jennifer A.; Campbell, Archie; Carmi, Shai; Caulfield, Mark J.; Cesarini, David; Chambers, John C.; Chandak, Giriraj Ratan; Cheng, Ching-Yu; Ciullo, Marina; Cornelis, Marilyn; Cusi, Daniele; Smith, George Davey; Deary, Ian J.; Dorajoo, Rajkumar; van Duijn, Cornelia M.; Ellinghaus, David; Erdmann, Jeanette; Eriksson, Johan G.; Evangelou, Evangelos; Evans, Michele K.; Faul, Jessica D.; Feenstra, Bjarke; Feitosa, Mary; Foisy, Sylvain; Franke, Andre; Friedlander, Yechiel; Gasparini, Paolo; Gieger, Christian; Gonzalez, Clicerio; Goyette, Philippe; Grant, Struan F. A.; Griffiths, Lyn R.; Groop, Leif; Gudnason, Vilmundur; Gyllensten, Ulf; Hakonarson, Hakon; Hamsten, Anders; van der Harst, Pim; Heng, Chew-Kiat; Hicks, Andrew A.; Hochner, Hagit; Huikuri, Heikki; Hunt, Steven C.; Jaddoe, Vincent W. V.; De Jager, Philip L.; Johannesson, Magnus; Johansson, Asa; Jonas, Jost B.; Jukema, J. Wouter; Junttila, Juhani; Kaprio, Jaakko; Kardia, Sharon L. R.; Karpe, Fredrik; Kumari, Meena; Laakso, Markku; van der Laan, Sander W.; Lahti, Jari; Laudes, Matthias; Lea, Rodney A.; Lieb, Wolfgang; Lumley, Thomas; Martin, Nicholas G.; Marz, Winfried; Matullo, Giuseppe; McCarthy, Mark I.; Medland, Sarah E.; Merriman, Tony R.; Metspalu, Andres; Meyer, Brian F.; Mohlke, Karen L.; Montgomery, Grant W.; Mook-Kanamori, Dennis; Munroe, Patricia B.; North, Kari E.; Nyholt, Dale R.; O′ connell, Jeffery R.; Ober, Carole; Oldehinkel, Albertine J.; Palmas, Walter; Palmer, Colin; Pasterkamp, Gerard G.; Patin, Etienne; Pennell, Craig E.; Perusse, Louis; Peyser, Patricia A.; Pirastu, Mario; Polderman, Tinca J. C.; Porteous, David J.; Posthuma, Danielle; Psaty, Bruce M.; Rioux, John D.; Rivadeneira, Fernando; Rotimi, Charles; Rotter, Jerome I.; Rudan, Igor; Den Ruijter, Hester M.; Sanghera, Dharambir K.; Sattar, Naveed; Schmidt, Reinhold; Schulze, Matthias B.; Schunkert, Heribert; Scott, Robert A.; Shuldiner, Alan R.; Sim, Xueling; Small, Neil; Smith, Jennifer A.; Sotoodehnia, Nona; Tai, E-Shyong; Teumer, Alexander; Timpson, Nicholas J.; Toniolo, Daniela; Tregouet, David-Alexandre; Tuomi, Tiinamaija; Vollenweider, Peter; Wang, Carol A.; Weir, David R.; Whitfield, John B.; Wijmenga, Cisca; Wong, Tien-Yin; Wright, John; Yang, Jingyun; Yu, Lei; Zemel, Babette S.; Zonderman, Alan B.; Perola, Markus; Magnusson, Patrik K. E.; Uitterlinden, Andre G.; Kooner, Jaspal S.; Chasman, Daniel I.; Loos, Ruth J. F.; Franceschini, Nora; Franke, Lude; Haley, Chris S.; Hayward, Caroline; Walters, Robin G.; Perry, John R. B.; Esko, Tonu; Helgason, Agnar; Stefansson, Kari; Joshi, Peter K.; Kubo, Michiaki; Wilson, James F.; Clark, David W.; Okada, Yukinori; Moore, Kristjan H. S.; Mason, Dan; Pirastu, Nicola; Gandin, Ilaria; Mattsson, Hannele; Barnes, Catriona L. K.; Lin, Kuang; Zhao, Jing Hua; Deelen, Patrick; Rohde, Rebecca; Schurmann, Claudia; Guo, Xiuqing; Giulianini, Franco; Zhang, Weihua; Medina-Gomez, Carolina; Karlsson, Robert; Bao, Yanchun; Bartz, Traci M.; Baumbach, Clemens; Biino, Ginevra; Bixley, Matthew J.; Brumat, Marco; Chai, Jin-Fang; Corre, Tanguy; Cousminer, Diana L.; Dekker, Annelot M.; Eccles, David A.; Van Eijk, Kristel R.; Fuchsberger, Christian; Gao, He; Germain, Marine; Gordon, Scott D.; de Haan, Hugoline G.; Harris, Sarah E.; Hofer, Edith; Huerta-Chagoya, Alicia; Igartua, Catherine; Jansen, Iris E.; Jia, Yucheng; Kacprowski, Tim; Karlsson, Torgny; Kleber, Marcus E.; Li, Shengchao Alfred; Li-Gao, Ruifang; Mahajan, Anubha; Matsuda, Koichi; Meidtner, Karina; Meng, Weihua; Montasser, May E.; van der Most, Peter J.; Munz, Matthias; Nutile, Teresa; Palviainen, Teemu; Prasad, Gauri; Prasad, Rashmi B.; Priyanka, Tallapragada Divya Sri; Rizzi, Federica; Salvi, Erika; Sapkota, Bishwa R.; Shriner, Daniel; Skotte, Line; Smart, Melissa C.; Smith, Albert Vernon; van der Spek, Ashley; Spracklen, Cassandra N.; Strawbridge, Rona J.; Tajuddin, Salman M.; Trompet, Stella; Turman, Constance; Verweij, Niek; Viberti, Clara; Wang, Lihua; Warren, Helen R.; Wootton, Robyn E.; Yanek, Lisa R.; Yao, Jie; Yousri, Noha A.; Zhao, Wei; Adeyemo, Adebowale A.; Afaq, Saima; Alberto Aguilar-Salinas, Carlos; Akiyama, Masato; Albert, Matthew L.; Allison, Matthew A.; Alver, Maris; Aung, Tin; Azizi, Fereidoun; Bentley, Amy R.; Boeing, Heiner; Boerwinkle, Eric; Borja, Judith B.; de Borst, Gert J.; Bottinger, Erwin P.; Broer, Linda; Campbell, Harry; Chanock, Stephen; Chee, Miao-Li; Chen, Guanjie; Chen, Yii-Der I.; Chen, Zhengming; Chiu, Yen-Feng; Cocca, Massimiliano; Collins, Francis S.; Concas, Maria Pina; Corley, Janie; Cugliari, Giovanni; Van Dam, Rob M.; Damulina, Anna; Daneshpour, Maryam S.; Day, Felix R.; Delgado, Graciela E.; Dhana, Klodian; Doney, Alexander S. F.; Doerr, Marcus; Doumatey, Ayo P.; Dzimiri, Nduna; Ebenesersdottir, S. Sunna; Elliott, Joshua; Elliott, Paul; Ewert, Ralf; Felix, Janine F.; Fischer, Krista; Freedman, Barry I.; Girotto, Giorgia; Goel, Anuj; Gogele, Martin; Goodarzi, Mark O.; Graff, Mariaelisa; Granot-Hershkovitz, Einat; Grodstein, Francine; Guarrera, Simonetta; Gudbjartsson, Daniel F.; Guity, Kamran; Gunnarsson, Bjarni; Guo, Yu; Hagenaars, Saskia P.; Haiman, Christopher A.; Halevy, Avner; Harris, Tamara B.; Hedayati, Mehdi; van Heel, David A.; Hirata, Makoto; Hofer, Imo; Hsiung, Chao Agnes; Huang, Jinyan; Hung, Yi-Jen; Ikram, M. Arfan; Jagadeesan, Anuradha; Jousilahti, Pekka; Kamatani, Yoichiro; Kanai, Masahiro; Kerrison, Nicola D.; Kessler, Thorsten; Khaw, Kay-Tee; Khor, Chiea Chuen; de Kleijn, Dominique P. V.; Koh, Woon-Puay; Kolcic, Ivana; Kraft, Peter; Kramer, Bernhard K.; Kutalik, Zoltan; Kuusisto, Johanna; Langenberg, Claudia; Launer, Lenore J.; Lawlor, Deborah A.; Lee, I-Te; Lee, Wen-Jane; Lerch, Markus M.; Li, Liming; Liu, Jianjun; Loh, Marie; London, Stephanie J.; Loomis, Stephanie; Lu, Yingchang; Luan, Jian′ an; Magi, Reedik; Manichaikul, Ani W.; Manunta, Paolo; Masson, Gisli; Matoba, Nana; Mei, Xue W.; Meisinger, Christa; Meitinger, Thomas; Mezzavilla, Massimo; Milani, Lili; Millwood, Iona Y.; Momozawa, Yukihide; Moore, Amy; Morange, Pierre-Emmanuel; Moreno-Macias, Hortensia; Mori, Trevor A.; Morrison, Alanna C.; Muka, Taulant; Murakami, Yoshinori; Murray, Alison D.; de Mutsert, Renee; Mychaleckyj, Josyf C.; Nalls, Mike A.; Nauck, Matthias; Neville, Matt J.; Nolte, Ilja M.; Ong, Ken K.; Orozco, Lorena; Padmanabhan, Sandosh; Palsson, Gunnar; Pankow, James S.; Pattaro, Cristian; Pattie, Alison; Polasek, Ozren; Poulter, Neil; Pramstaller, Peter P.; Quintana-Murci, Lluis; Raikkonen, Katri; Ralhan, Sarju; Rao, Dabeeru C.; van Rheenen, Wouter; Rich, Stephen S.; Ridker, Paul M.; Rietveld, Cornelius A.; Robino, Antonietta; van Rooij, Frank J. A.; Ruggiero, Daniela; Saba, Yasaman; Sabanayagam, Charumathi; Sabater-Lleal, Maria; Felicita Sala, Cinzia; Salomaa, Veikko; Sandow, Kevin; Schmidt, Helena; Scott, Laura J.; Scott, William R.; Sedaghati-Khayat, Bahareh; Sennblad, Bengt; van Setten, Jessica; Sever, Peter J.; Sheu, Wayne H-H; Shi, Yuan; Shrestha, Smeeta; Shukla, Sharvari Rahul; Sigurdsson, Jon K.; Sikka, Timo Tonis; Singh, Jai Rup; Smith, Blair H.; Stancakova, Alena; Stanton, Alice; Starr, John M.; Stefansdottir, Lilja; Straker, Leon; Sulem, Patrick; Sveinbjornsson, Gardar; Swertz, Morris A.; Taylor, Adele M.; Taylor, Kent D.; Terzikhan, Natalie; Tham, Yih-Chung; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tillander, Annika; Tracy, Russell P.; Tusie-Luna, Teresa; Tzoulaki, Ioanna; Vaccargiu, Simona; Vangipurapu, Jagadish; Veldink, Jan H.; Vitart, Veronique; Volker, Uwe; Vuoksimaa, Eero; Wakil, Salma M.; Waldenberger, Melanie; Wander, Gurpreet S.; Wang, Ya Xing

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INBREEDING DEPRESSION HOMOZYGOSITY FERTILITY LOCI RUNS QUANTIFICATION

Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease 期刊论文
NATURE GENETICS, 2017, 卷号: 49, 期号: 12, 页码: 1722-+
Authors: Lu, Xiangfeng; Peloso, Gina M.; Liu, Dajiang J.; Wu, Ying; Zhang, He; Zhou, Wei; Li, Jun; Tang, Clara Sze-man; Dorajoo, Rajkumar; Li, Huaixing; Long, Jirong; Guo, Xiuqing; Xu, Ming; Spracklen, Cassandra N.; Chen, Yang; Liu, Xuezhen; Zhang, Yan; Khor, Chiea Chuen; Liu, Jianjun; Sun, Liang; Wang, Laiyuan; Gao, Yu-Tang; Hu, Yao; Yu, Kuai; Wang, Yiqin; Cheung, Chloe Yu Yan; Wang, Feijie; Huang, Jianfeng; Fan, Qiao; Cai, Qiuyin; Chen, Shufeng; Shi, Jinxiu; Yang, Xueli; Zhao, Wanting; Sheu, Wayne H-H; Cherny, Stacey Shawn; He, Meian; Feranil, Alan B.; Adair, Linda S.; Gordon-Larsen, Penny; Du, Shufa; Varma, Rohit; Chen, Yii-Der Ida; Shu, Xiao-Ou; Lam, Karen Siu Ling; Wong, Tien Yin; Ganesh, Santhi K.; Mo, Zengnan; Hveem, Kristian; Fritsche, Lars G.; Nielsen, Jonas Bille; Tse, Hung-fat; Huo, Yong; Cheng, Ching-Yu; Chen, Y. Eugene; Zheng, Wei; Tai, E. Shyong; Gao, Wei; Lin, Xu; Huang, Wei; Abecasis, Goncalo; Kathiresan, Sekar; Mohlke, Karen L.; Wu, Tangchun; Sham, Pak Chung; Gu, Dongfeng; Willer, Cristen J.; GLGC Consortium; Sham, Pak Chung(30,31,32); Gu, Dongfeng(1,2); Willer, Cristen J.(3,4,9)

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Identification of new susceptibility loci for IgA nephropathy in Han Chinese 期刊论文
NATURE COMMUNICATIONS, 2015, 卷号: 6
Authors: Li, Ming; Foo, Jia-Nee; Wang, Jin-Quan; Low, Hui-Qi; Tang, Xue-Qing; Toh, Kai-Yee; Yin, Pei-Ran; Khor, Chiea-Chuen; Goh, Yu-Fen; Irwan, Ishak D.; Xu, Ri-Cong; Andiappan, Anand K.; Bei, Jin-Xin; Rotzschke, Olaf; Chen, Meng-Hua; Cheng, Ching-Yu; Sun, Liang-Dan; Jiang, Geng-Ru; Wong, Tien-Yin; Lin, Hong-Li; Aung, Tin; Liao, Yun-Hua; Saw, Seang-Mei; Ye, Kun; Ebstein, Richard P.; Chen, Qin-Kai; Shi, Wei; Chew, Soo-Hong; Chen, Jian; Zhang, Fu-Ren; Li, Sheng-Ping; Xu, Gang; Tai, E. Shyong; Wang, Li; Chen, Nan; Zhang, Xue-Jun; Zeng, Yi-Xin; Zhang, Hong; Liu, Zhi-Hong; Yu, Xue-Qing; Liu, Jian-Jun

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Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations 期刊论文
NATURE COMMUNICATIONS, 2015, 卷号: 6
Authors: Huang, Lv-Zhen; Li, Ying-Jie; Xie, Xue-Feng; Zhang, Jing-Jing; Cheng, Ching-Yu; Yamashiro, Kenji; Chen, Li-Jia; Ma, Xiao-Yun; Cheung, Chui Ming G.; Wang, Yu-Sheng; Zhang, Chun-Fang; Bai, Yu-Jing; Hou, Jing; Chen, Xiao-Li; Qi, Yun; Li, Shan-Shan; Sun, Yao-Yao; Mei, Jun-Pu; Cheng, Yong; Yu, Wen-Zhen; Hu, Xiong-Bing; Zhuang, Feng-Feng; Fan, Lei; Lu, Yi; Sun, Xing-Huai; Zhu, Xiang-Jia; Shen, De-Fen; Chan, Chi-Chao; Zhao, Ming-Wei; Yoshimura, Nagahisa; Pang, Chi Pui; Wong, Tien Yin; Khor, Chiea Chuen; Zhang, Kang; Zhou, Peng; Li, Xiao-Xin

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New loci and coding variants confer risk for age-related macular degeneration in East Asians 期刊论文
NATURE COMMUNICATIONS, 2015, 卷号: 6
Authors: Cheng, Ching-Yu; Yamashiro, Kenji; Chen, Li Jia; Ahn, Jeeyun; Huang, Lulin; Huang, Lvzhen; Cheung, Chui Ming G.; Miyake, Masahiro; Cackett, Peter D.; Yeo, Ian Y.; Laude, Augustinus; Mathur, Ranjana; Pang, Junxiong; Sim, Kar Seng; Koh, Adrian H.; Chen, Peng; Lee, Shu Yen; Wong, Doric; Chan, Choi Mun; Loh, Boon Kwang; Sun, Yaoyao; Davila, Sonia; Nakata, Isao; Nakanishi, Hideo; Akagi-Kurashige, Yumiko; Gotoh, Norimoto; Tsujikawa, Akitaka; Matsuda, Fumihiko; Mori, Keisuke; Yoneya, Shin; Sakurada, Yoichi; Iijima, Hiroyuki; Iida, Tomohiro; Honda, Shigeru; Lai, Timothy Yuk Yau; Tam, Pancy Oi Sin; Chen, Haoyu; Tang, Shibo; Ding, Xiaoyan; Wen, Feng; Lu, Fang; Zhang, Xiongze; Shi, Yi; Zhao, Peiquan; Zhao, Bowen; Sang, Jinghong; Gong, Bo; Dorajoo, Rajkumar; Yuan, Jian-Min; Koh, Woon-Puay; van Dam, Rob M.; Friedlander, Yechiel; Lin, Ying; Hibberd, Martin L.; Foo, Jia Nee; Wang, Ningli; Wong, Chang Hua; Tan, Gavin S.; Park, Sang Jun; Bhargava, Mayuri; Gopal, Lingam; Naing, Thet; Liao, Jiemin; Ong, Peng Guan; Mitchell, Paul; Zhou, Peng; Xie, Xuefeng; Liang, Jinlong; Mei, Junpu; Jin, Xin; Saw, Seang-Mei; Ozaki, Mineo; Mizoguchi, Takanori; Kurimoto, Yasuo; Woo, Se Joon; Chung, Hum; Yu, Hyeong-Gon; Shin, Joo Young; Park, Dong Ho; Kim, In Taek; Chang, Woohyok; Sagong, Min; Lee, Sang-Joon; Kim, Hyun Woong; Lee, Ji Eun; Li, Yi; Liu, Jianjun; Teo, Yik Ying; Heng, Chew Kiat; Lim, Tock Han; Yang, Suk-Kyun; Song, Kyuyoung; Vithana, Eranga N.; Aung, Tin; Bei, Jin Xin; Zeng, Yi Xin; Tai, E. Shyong; Li, Xiao Xin; Yang, Zhenglin; Park, Kyu-Hyung; Pang, Chi Pui; Yoshimura, Nagahisa; Wong, Tien Yin; Khor, Chiea Chuen

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Different Hereditary Contribution of the CFH Gene Between Polypoidal Choroidal Vasculopathy and Age-Related Macular Degeneration in Chinese Han People 期刊论文
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2014, 卷号: 55, 期号: 4, 页码: 2534-2538
Authors: Huang, Lvzhen; Li, Yingjie; Guo, Shicheng; Sun, Yaoyao; Zhang, Chunfang; Bai, Yujing; Li, Shanshan; Yang, Fei; Zhao, Min; Wang, Bin; Yu, Wenzhen; Zhao, Mingwei; Khor, Chiea Chuen; Li, Xiaoxin

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Neovascular Age-related Macular Degeneration Polypoidal Choroidal Vasculopathy Complement Factor h Single-nucleotide Polymorphism

rs4711751 and rs1999930 Are Not Associated with Neovascular Age-Related Macular Degeneration or Polypoidal Choroidal Vasculopathy in the Chinese Population 期刊论文
OPHTHALMIC RESEARCH, 2014, 卷号: 52, 期号: 2, 页码: 102-106
Authors: Huang, Lvzhen; Li, Mingwu; Ma, Xiaoyun; Li, Yingjie; Zhang, Chunfang; Sun, Yaoyao; Bai, Yujing; Wang, Bin; Yu, Wenzhen; Zhao, Mingwei; Khor, Chiea Chuen; Li, Xiaoxin

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Age-related Macular Degeneration Polypoidal Choroidal Vasculopathy Gene Polymorphism Rs1999930 Rs4711751

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