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Trap and kill strategy for non-BRCA mutant pancreatic cancer by co-delivery of olaparib and JQ1 with plectin-1 targeting peptide nanoparticles 期刊论文
NANO TODAY, 2020, 卷号: 33, 页码: -
Authors:  Wang, Yazhou;  Du, Chong;  Zhao, Ying;  Nie, Guangjun;  Yang, Yinmo
Favorite  |  View/Download:0/0  |  Submit date:2021/03/09
non-BRCA mutation  MUTATION CARRIERS  pancreatic cancer  PARP INHIBITOR  plectin-1 targeting peptidenanoparticles  EFFICACY  drug delivery  trap and kill strategy  
Combination of tumour-infarction therapy and chemotherapy via the co-delivery of doxorubicin and thrombin encapsulated in tumour-targeted nanoparticles 期刊论文
NATURE BIOMEDICAL ENGINEERING, 2020, 卷号: 4, 期号: 7, 页码: 732-742
Authors:  Li, Suping;  Zhang, Yinlong;  Ho, Shih-Hsin;  Li, Bozhao;  Wang, Meifang;  Deng, Xiongwei;  Yang, Na;  Liu, Guangna;  Lu, Zefang;  Xu, Junchao;  Shi, Quanwei;  Han, Jing-Yan;  Zhang, Lirong;  Wu, Yan;  Zhao, Yuliang;  Nie, Guangjun
Favorite  |  View/Download:1/0  |  Submit date:2021/03/09
TISSUE FACTOR  IN-VIVO  CANCER  VASCULATURE  STRATEGIES  CHITOSAN  MICE  
Gold Nanoparticles for Targeting the Fibrotic Heart: A Probe Indicating Vascular Permeability 期刊论文
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2019, 卷号: 19, 期号: 12, 页码: 7546-7550
Authors:  Yang, Chengzhi;  Tian, Aiju;  Wu, Jimin;  Meng, Zenghui;  Zhang, Youyi;  Nie, Guangjun;  Li, Zijian
Favorite  |  View/Download:4/0  |  Submit date:2019/08/26
Cardiac Fibrosis  Fibrosis  Cardiac Inflammation  Inflammation  Gold Nanoparticles  Mechanisms  Vascular Permeability  Cancer  
Epidermal Growth Factor Receptor-Targeting Peptide Nanoparticles Simultaneously Deliver Gemcitabine and Olaparib To Treat Pancreatic Cancer with Breast Cancer 2 (BRCA2) Mutation 期刊论文
ACS NANO, 2018, 卷号: 12, 期号: 11, 页码: 10785-10796
Authors:  Du, Chong;  Qi, Yingqiu;  Zhang, Yinlong;  Wang, Yazhou;  Zhao, Xiao;  Min, Huan;  Han, Xuexiang;  Lang, Jiayan;  Qin, Hao;  Shi, Quanwei;  Zhang, Zhengkui;  Tian, Xiaodong;  Anderson, Greg J.;  Zhao, Ying;  Nie, Guangjun;  Yang, Yinmo
Favorite  |  View/Download:3/0  |  Submit date:2019/01/02
pancreatic cancer  BRCA2 mutation  synthetic lethality  drug co-delivery  self-assembly peptide nanoparticle  
A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo 期刊论文
NATURE BIOTECHNOLOGY, 2018, 卷号: 36, 期号: 3, 页码: 258-+
Authors:  Li, Suping;  Jiang, Qiao;  Liu, Shaoli;  Zhang, Yinlong;  Tian, Yanhua;  Song, Chen;  Wang, Jing;  Zou, Yiguo;  Anderson, Gregory J.;  Han, Jing-Yan;  Chang, Yung;  Liu, Yan;  Zhang, Chen;  Chen, Liang;  Zhou, Guangbiao;  Nie, Guangjun;  Yan, Hao;  Ding, Baoquan;  Zhao, Yuliang;  Nie, Guangjun(1,2);  Yan, Hao(7,8);  Ding, Baoquan(1,2);  Zhao, Yuliang(1,2)
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Chaperonin-GroEL as a Smart Hydrophobic Drug Delivery and Tumor Targeting Molecular Machine for Tumor Therapy 期刊论文
NANO LETTERS, 2018, 卷号: 18, 期号: 2, 页码: 921-928
Authors:  Yuan, Yi;  Du, Chong;  Sun, Cuiji;  Zhu, Jin;  Wu, Shan;  Zhang, Yinlong;  Ji, Tianjiao;  Lei, Jianlin;  Yang, Yinmo;  Gao, Ning;  Nie, Guangjun
Favorite  |  View/Download:20/0  |  Submit date:2018/05/17
Chaperonin  Groel  Nanocarrier  Atp Excitation  Hydrophobic Drug Delivery  Tumor Targeting  
Nanoparticle-mediated local depletion of tumour-associated platelets disrupts vascular barriers and augments drug accumulation in tumours 期刊论文
NATURE BIOMEDICAL ENGINEERING, 2017, 卷号: 1, 期号: 8, 页码: 667-679
Authors:  Li, Suping;  Zhang, Yinlong;  Wang, Jing;  Zhao, Ying;  Ji, Tianjiao;  Zhao, Xiao;  Ding, Yanping;  Zhao, Xiaozheng;  Zhao, Ruifang;  Li, Feng;  Yang, Xiao;  Liu, Shaoli;  Liu, Zhaofei;  Lai, Jianhao;  Whittaker, Andrew K.;  Anderson, Gregory J.;  Wei, Jingyan;  Nie, Guangjun;  Nie, Guangjun(1,7)
Adobe PDF(4780Kb)  |  Favorite  |  View/Download:13/0  |  Submit date:2018/03/15
pHLIP-mediated targeting of truncated tissue factor to tumor vessels causes vascular occlusion and impairs tumor growth 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 27, 页码: 23523-23532
Authors:  Li, Suping;  Tian, Yanhua;  Zhao, Ying;  Zhang, Yinlong;  Su, Shishuai;  Wang, Jing;  Wu, Meiyu;  Shi, Quanwei;  Anderson, Gregory J.;  Thomsen, Johannes;  Zhao, Ruifang;  Ji, Tianjiao;  Wang, Jie;  Nie, Guangjun
Favorite  |  View/Download:12/0  |  Submit date:2016/11/07
Ph Low Insertion Peptide (Phlip)  Truncated Tissue Factor (Ttf)  Tumor Vessel Targeting  Thrombosis  
Identification of four SLC19A2 mutations in four Chinese thiamine responsive megaloblastic anemia patients without diabetes 期刊论文
BLOOD CELLS MOLECULES AND DISEASES, 2014, 卷号: 52, 期号: 4, 页码: 203-204
Authors:  Liu, Gang;  Yang, Fan;  Han, Bing;  Liu, Junxiu;  Nie, Guangjun
Favorite  |  View/Download:5/0  |  Submit date:2016/10/21
No overt structural or functional changes associated with PEG-coated gold nanoparticles accumulation with acute exposure in the mouse heart 期刊论文
TOXICOLOGY LETTERS, 2013, 卷号: 222, 期号: 2, 页码: 197-203
Authors:  Yang, Chengzhi;  Yang, Hui;  Wu, Jimin;  Meng, Zenghui;  Xing, Rui;  Tian, Aiju;  Tian, Xin;  Guo, Lijun;  Zhang, Youyi;  Nie, Guangjun;  Li, Zijian
Favorite  |  View/Download:8/0  |  Submit date:2016/11/08
Gold Nanoparticles  Heart  Cardiac Toxicity  Cardiac Remodeling