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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders 期刊论文
AMERICAN JOURNAL OF HUMAN GENETICS, 2018, 卷号: 103, 期号: 5, 页码: 691-706
Authors:  Ligthart, Symen;  Vaez, Ahmad;  Vosa, Urmo;  Stathopoulou, Maria G.;  de Vries, Paul S.;  Prins, Bram P.;  Van der Most, Peter J.;  Tanaka, Toshiko;  Naderi, Elnaz;  Rose, Lynda M.;  Wu, Ying;  Karlsson, Robert;  Barbalic, Maja;  Lin, Honghuang;  Pool, Rene;  Zhu, Gu;  Mace, Aurelien;  Sidore, Carlo;  Trompet, Stella;  Mangino, Massimo;  Sabater-Lleal, Maria;  Kemp, John P.;  Abbasi, Ali;  Kacprowski, Tim;  Verweij, Niek;  Smith, Albert V.;  Huang, Tao;  Marzi, Carola;  Feitosa, Mary F.;  Lohman, Kurt K.;  Kleber, Marcus E.;  Milaneschi, Yuri;  Mueller, Christian;  Huq, Mahmudul;  Vlachopoulou, Efthymia;  Lyytikainen, Leo-Pekka;  Oldmeadow, Christopher;  Deelen, Joris;  Perola, Markus;  Zhao, Jing Hua;  Feenstra, Bjarke;  Amini, Marzyeh;  Lahti, Jari;  Schraut, Katharina E.;  Fornage, Myriam;  Suktitipat, Bhoom;  Chen, Wei-Min;  Li, Xiaohui;  Nutile, Teresa;  Malerba, Giovanni;  Luan, Jian′  an;  Bak, Tom;  Schork, Nicholas;  Del Greco, Fabiola M.;  Thiering, Elisabeth;  Mahajan, Anubha;  Marioni, Riccardo E.;  Mihailov, Evelin;  Eriksson, Joel;  Ozel, Ayse Bilge;  Zhang, Weihua;  Nethander, Maria;  Cheng, Yu-Ching;  Aslibekyan, Stella;  Ang, Wei;  Gandin, Ilaria;  Yengo, Loic;  Portas, Laura;  Kooperberg, Charles;  Hofer, Edith;  Rajan, Kumar B.;  Schurmann, Claudia;  den Hollander, Wouter;  Ahluwalia, Tarunveer S.;  Zhao, Jing;  Draisma, Harmen H. M.;  Ford, Ian;  Timpson, Nicholas;  Teumer, Alexander;  Huang, Hongyan;  Wahl, Simone;  Liu, YongMei;  Huang, Jie;  Uh, Hae-Won;  Geller, Frank;  Joshi, Peter K.;  Yanek, Lisa R.;  Trabetti, Elisabetta;  Lehne, Benjamin;  Vozzi, Diego;  Verbanck, Marie;  Biino, Ginevra;  Saba, Yasaman;  Meulenbelt, Ingrid;  O′  Connell, Jeff R.;  Laakso, Markku;  Giulianini, Franco;  Magnusson, Patrik K. E.;  Ballantyne, Christie M.;  Hottenga, Jouke Jan;  Montgomery, GrantW.;  Rivadineira, Fernando;  Rueedi, Rico;  Steri, Maristella;  Herzig, Karl-Heinz;  Stott, David J.;  Menni, Cristina;  Franberg, Mattias;  St Pourcain, Beate;  Felix, Stephan B.;  Pers, Tune H.;  Bakker, Stephan J. L.;  Kraft, Peter;  Peters, Annette;  Vaidya, Dhananjay;  Delgado, Graciela;  Smit, Johannes H.;  Grossmann, Vera;  Sinisalo, Juha;  Seppala, Ilkka;  Williams, Stephen R.;  Holliday, Elizabeth G.;  Moed, Matthijs;  Langenberg, Claudia;  Raikkonen, Katri;  Ding, Jingzhong;  Campbell, Harry;  Sale, Michele M.;  Chen, Yii-Der I.;  James, Alan L.;  Ruggiero, Daniela;  Soranzo, Nicole;  Hartman, Catharina A.;  Smith, Erin N.;  Berenson, Gerald S.;  Fuchsberger, Christian;  Hernandez, Dena;  Tiesler, Carla M. T.;  Giedraitis, Vilmantas;  Liewald, David;  Fischer, Krista;  Mellstrom, Dan;  Larsson, Anders;  Wang, Yunmei;  Scott, William R.;  Lorentzon, Matthias;  Beilby, John;  Ryan, Kathleen A.;  Pennell, Craig E.;  Vuckovic, Dragana;  Balkau, Beverly;  Concas, Maria Pina;  Schmidt, Reinhold;  de Leon, Carlos F. Mendes;  Bottinger, Erwin P.;  Kloppenburg, Margreet;  Paternoster, Lavinia;  Boehnke, Michael;  Musk, A. W.;  Willemsen, Gonneke;  Evans, David M.;  Madden, Pamela A. F.;  Kahonen, Mika;  Kutalik, Zoltan;  Zoledziewska, Magdalena;  Karhunen, Ville;  Kritchevsky, Stephen B.;  Sattar, Naveed;  Lachance, Genevieve;  Clarke, Robert;  Harris, Tamara B.;  Raitakari, Olli T.;  Attia, John R.;  Van Heemst, Diana;  Kajantie, Eero;  Sorice, Rossella;  Gambaro, Giovanni;  Scott, Robert A.;  Hicks, Andrew A.;  Ferrucci, Luigi;  Standl, Marie;  Lindgren, Cecilia M.;  Starr, John M.;  Karlsson, Magnus;  Lind, Lars;  Li, Jun Z.;  Chambers, John C.;  Mori, Trevor A.;  de Geus, Eco J. C. N.;  Heath, Andrew C.;  Martin, Nicholas G.;  Auvinen, Juha;  Buckley, Brendan M.;  de Craen, Anton J. M.;  Waldenberger, Melanie;  Strauch, Konstantin;  Meitinger, Thomas;  Scott, Rodney J.;  McEvoy, Mark;  Beekman, Marian;  Bombieri, Cristina;  Ridker, Paul M.;  Mohlke, Karen L.;  Pedersen, Nancy L.;  Morrison, Alanna C.;  Boomsma, Dorret I.;  Whitfield, John B.;  Strachan, David P.;  Hofman, Albert;  Vollenweider, Peter;  Cucca, Francesco;  Jarvelin, Marjo-Riitta;  Jukema, J. Wouter;  Spector, Tim D.;  Hamsten, Anders;  Zeller, Tanja;  Uitterlinden, Andre G.;  Nauck, Matthias;  Gudnason, Vilmundur;  Qi, Lu;  Grallert, Harald;  Borecki, Ingrid B.;  Rotter, Jerome I.;  Maerz, Winfried;  Wild, Philipp S.;  Lokki, Marja-Liisa;  Boyle, Michael;  Salomaa, Veikko;  Melbye, Mads;  Eriksson, Johan G.;  Wilson, James F.;  Penninx, Brenda W. J. H.;  Becker, Diane M.;  Worrall, Bradford B.;  Gibson, Greg;  Krauss, Ronald M.;  Ciullo, Marina;  Zaza, Gianluigi;  Wareham, Nicholas J.;  Oldehinkel, Albertine J.;  Palmer, Lyle J.;  Murray, Sarah S.;  Pramstaller, Peter P.;  Bandinelli, Stefania;  Heinrich, Joachim;  Ingelsson, Erik;  Deary, Ian J.;  Magi, Reedik;  Vandenput, Liesbeth;  van der Harst, Pim;  Desch, Karl C.;  Kooner, Jaspal S.;  Ohlsson, Claes;  Hayward, Caroline;  Lehtimaki, Terho;  Shuldiner, Alan R.;  Arnett, Donna K.;  Beilin, Lawrence J.;  Robino, Antonietta;  Froguel, Philippe;  Pirastu, Mario;  Jess, Tine;  Koenig, Wolfgang;  Loos, Ruth J. F.;  Evans, Denis A.;  Schmidt, Helena;  Smith, George Davey;  Slagboom, P. Eline;  Eiriksdottir, Gudny;  Morris, Andrew P.;  Psaty, Bruce M.;  Tracy, Russell P.;  Nolte, Ilja M.;  Boerwinkle, Eric;  Visvikis-Siest, Sophie;  Reiner, Alex P.;  Gross, Myron;  Bis, Joshua C.;  Franke, Lude;  Franco, Oscar H.;  Benjamin, Emelia J.;  Chasman, Daniel I.;  Dupuis, Josee;  Snieder, Harold;  Dehghan, Abbas;  Alizadeh, Behrooz Z.;  LifeLines Cohort Study;  CHARGE Inflammation Working Grp();  Dehghan, Abbas(1,191);  Alizadeh, Behrooz Z.(2)
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Common susceptibility variants are shared between schizophrenia and psoriasis in the Han Chinese population 期刊论文
JOURNAL OF PSYCHIATRY & NEUROSCIENCE, 2016, 卷号: 41, 期号: 6, 页码: 413-421
Authors:  Yin, Xianyong;  Wineinger, Nathan E.;  Wang, Kai;  Yue, Weihua;  Norgren, Nina;  Wang, Ling;  Yao, Weiyi;  Jiang, Xiaoyun;  Wu, Bo;  Cui, Yong;  Shen, Changbing;  Cheng, Hui;  Zhou, Fusheng;  Chen, Gang;  Zuo, Xianbo;  Zheng, Xiaodong;  Fan, Xing;  Wang, Hongyan;  Wang, Lifang;  Lee, Jimmy;  Lam, Max;  Tai, E. Shyong;  Zhang, Zheng;  Huang, Qiong;  Sun, Liangdan;  Xu, Jinhua;  Yang, Sen;  Wilhelmsen, Kirk C.;  Liu, Jianjun;  Schork, Nicholas J.;  Zhang, Xuejun
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Gene expression analysis of head and neck squamous cell carcinoma survival and recurrence 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 1, 页码: 547-555
Authors:  Zhi, Xu;  Lamperska, Katarzyna;  Golusinski, Pawel;  Schork, Nicholas J.;  Luczewski, Lukasz;  Kolenda, Tomasz;  Golusinski, Wojciech;  Masternak, Michal M.
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Pcr Array  Cancer Pathway  Gene Expression  Oral Cancer  
Expression levels of insulin-like growth factors 1 and 2 in head and neck squamous cell carcinoma 期刊论文
GROWTH HORMONE & IGF RESEARCH, 2014, 卷号: 24, 期号: 4, 页码: 137-141
Authors:  Zhi, Xu;  Lamperska, Katarzyna;  Golusinski, Pawel;  Schork, Nicholas J.;  Luczewski, Lukasz;  Golusinski, Wojciech;  Masternak, Michal M.
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Oral Cancer  Igf1  Igf2  Survival  
Human dopamine beta-hydroxylase (DBH) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure 期刊论文
JOURNAL OF HYPERTENSION, 2010, 卷号: 28, 期号: 1, 页码: 76-U26
Authors:  Chen, Yuqing;  Wen, Gen;  Rao, Fangwen;  Zhang, Kuixing;  Wang, Lei;  Rodriguez-Flores, Juan L.;  Sanchez, Amber P.;  Mahata, Manjula;  Taupenot, Laurent;  Sun, Ping;  Mahata, Sushil K.;  Tayo, Bamidele;  Schork, Nicholas J.;  Ziegler, Michael G.;  Hamilton, Bruce A.;  O′  Connor, Daniel T.
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Dopamine Beta-hydroxylase  Hypertension  Polymorphism  
Progression of Chronic Kidney Disease: Adrenergic Genetic Influence on Glomerular Filtration Rate Decline in Hypertensive Nephrosclerosis 期刊论文
AMERICAN JOURNAL OF NEPHROLOGY, 2010, 卷号: 32, 期号: 1, 页码: 23-30
Authors:  Chen, Yuqing;  Lipkowitz, Michael S.;  Salem, Rany M.;  Fung, Maple M.;  Bhatnagar, Vibha;  Mahata, Manjula;  Nievergelt, Caroline M.;  Rao, Fangwen;  Mahata, Sushil K.;  Schork, Nicholas J.;  Hicks, Pamela J.;  Bowden, Donald W.;  Freedman, Barry I.;  Brophy, Victoria H.;  O′  Connor, Daniel T.;  AASK Co Investigators
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Adrenergic Genetic Influence  African-american Study Of Kidney Disease  Chronic Kidney Disease  End-stage Renal Disease  Glomerular Filtration Rate  Hypertensive Nephrosclerosis  
Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis 期刊论文
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2009, 卷号: 24, 期号: 12, 页码: 3677-3686
Authors:  Fung, Maple M.;  Chen, Yuqing;  Lipkowitz, Michael S.;  Salem, Rany M.;  Bhatnagar, Vibha;  Mahata, Manjula;  Nievergelt, Caroline M.;  Rao, Fangwen;  Mahata, Sushil K.;  Schork, Nicholas J.;  Brophy, Victoria H.;  O′  Connor, Daniel T.;  AASK Co-Investigators
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Aask  African Americans  Glomerular Filtration Rate  Kidney Disease  Sympathetic Nervous System  
Naturally Occurring Human Genetic Variation in the 3 ′-Untranslated Region of the Secretory Protein Chromogranin A Is Associated With Autonomic Blood Pressure Regulation and Hypertension in a Sex-Dependent Fashion 期刊论文
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 卷号: 52, 期号: 18, 页码: 1468-1481
Authors:  Chen, Yuqing;  Rao, Fangwen;  Rodriguez-Flores, Juan L.;  Mahata, Manjula;  Fung, Maple M.;  Stridsberg, Mats;  Vaingankar, Sucheta M.;  Wen, Gen;  Salem, Rany M.;  Das, Madhusudan;  Cockburn, Myles G.;  Schork, Nicholas J.;  Ziegler, Michael G.;  Hamilton, Bruce A.;  Mahata, Sushil K.;  Taupenot, Laurent;  O′  Connor, Daniel T.
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Hypertension  Chromaffin  Catecholamine  Adrenal  Sympathetic