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ADAM15 expression is increased in lung CD8(+) T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction 期刊论文
RESPIRATORY RESEARCH, 2020, 卷号: 21, 期号: 1, 页码: -
Authors:  Wang, Xiaoyun;  Zhang, Duo;  Higham, Andrew;  Wolosianka, Sophie;  Gai, Xiaoyan;  Zhou, Lu;  Petersen, Hans;  Pinto-Plata, Victor;  Divo, Miguel;  Silverman, Edwin K.;  Celli, Bartolome;  Singh, Dave;  Sun, Yongchang;  Owen, Caroline A.
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COPD  SMOKE-INDUCED EMPHYSEMA  Cigarette smoke  PULMONARY-DISEASE  Macrophage  INFLAMMATION  CD8(+) T cell  ADAM-15  Epithelial cell  FAMILY  Forced expiratory volume in 1s  DISINTEGRIN  Airflow obstruction  METALLOPROTEINASES  DESTRUCTION  FIBROBLASTS  APOPTOSIS  
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries 期刊论文
NATURE GENETICS, 2019, 卷号: 51, 期号: 3, 页码: 481-+
Authors:  Shrine, Nick;  Guyatt, Anna L.;  Erzurumluoglu, A. Mesut;  Jackson, Victoria E.;  Hobbs, Brian D.;  Melbourne, Carl A.;  Batini, Chiara;  Fawcett, Katherine A.;  Song, Kijoung;  Sakornsakolpat, Phuwanat;  Li, Xingnan;  Boxall, Ruth;  Reeve, Nicola F.;  Obeidat, Ma′  en;  Zhao, Jing Hua;  Wielscher, Matthias;  Weiss, Stefan;  Kentistou, Katherine A.;  Cook, James P.;  Sun, Benjamin B.;  Zhou, Jian;  Hui, Jennie;  Karrasch, Stefan;  Imboden, Medea;  Harris, Sarah E.;  Marten, Jonathan;  Enroth, Stefan;  Kerr, Shona M.;  Surakka, Ida;  Vitart, Veronique;  Lehtimaki, Terho;  Allen, Richard J.;  Bakke, Per S.;  Beaty, Terri H.;  Bleecker, Eugene R.;  Bosse, Yohan;  Brandsma, Corry-Anke;  Chen, Zhengming;  Crapo, James D.;  Danesh, John;  DeMeo, Dawn L.;  Dudbridge, Frank;  Ewert, Ralf;  Gieger, Christian;  Gulsvik, Amund;  Hansell, Anna L.;  Hao, Ke;  Hoffman, Joshua D.;  Hokanson, John E.;  Homuth, Georg;  Joshi, Peter K.;  Joubert, Philippe;  Langenberg, Claudia;  Li, Xuan;  Li, Liming;  Lin, Kuang;  Lind, Lars;  Locantore, Nicholas;  Luan, Jian′  an;  Mahajan, Anubha;  Maranville, Joseph C.;  Murray, Alison;  Nickle, David C.;  Packer, Richard;  Parker, Margaret M.;  Paynton, Megan L.;  Porteous, David J.;  Prokopenko, Dmitry;  Qiao, Dandi;  Rawal, Rajesh;  Runz, Heiko;  Sayers, Ian;  Sin, Don D.;  Smith, Blair H.;  Artigas, Maria Soler;  Sparrow, David;  Tal-Singer, Ruth;  Timmers, Paul R. H. J.;  Van den Berge, Maarten;  Whittaker, John C.;  Woodruff, Prescott G.;  Verges-Armstrong, Laura M.;  Troyanskaya, Olga G.;  Raitakari, Olli T.;  Kahonenn, Mika;  Polasek, Ozren;  Gyllensten, Ulf;  Rudan, Igor;  Deary, Ian J.;  Probst-Hensch, Nicole M.;  Schulz, Holger;  James, Alan L.;  Wilson, James F.;  Stubbe, Beate;  Zeggini, Eleftheria;  Jarvelin, Marjo-Riitta;  Wareham, Nick;  Silverman, Edwin K.;  Hayward, Caroline;  Morris, Andrew P.;  Butterworth, Adam S.;  Scott, Robert A.;  Walters, Robin G.;  Meyers, Deborah A.;  Cho, Michael H.;  Strachan, David P.;  Hall, Ian P.;  Tobin, Martin D.;  Wain, Louise, V;  Understanding Soc Sci Grp()
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Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study 期刊论文
JAMA ONCOLOGY, 2017, 卷号: 3, 期号: 5, 页码: 636-651
Authors:  Haycock, Philip C.;  Burgess, Stephen;  Nounu, Aayah;  Zheng, Jie;  Okoli, George N.;  Bowden, Jack;  Wade, Kaitlin Hazel;  Timpson, Nicholas J.;  Evans, David M.;  Willeit, Peter;  Aviv, Abraham;  Gaunt, Tomr.;  Hemani, Gibran;  Mangino, Massimo;  Ellis, Hayley Patricia;  Kurian, Kathreena M.;  Pooley, Karen A.;  Eeles, Rosalind A.;  Lee, Jeffrey E.;  Fang, Shenying;  Chen, Wei V.;  Law, Matthew H.;  Bowdler, Lisa M.;  Iles, Mark M.;  Yang, Qiong;  Worrall, Bradford B.;  Markus, Hugh Stephen;  Hung, Rayjean J.;  Amos, Chris I.;  Spurdle, Amanda B.;  Thompson, Deborah J.;  O′  Mara, Tracy A.;  Wolpin, Brian;  Amundadottir, Laufey;  Stolzenberg-Solomon, Rachael;  Trichopoulou, Antonia;  Onland-Moret, Charlotte;  Lund, Eiliv;  Duell, Eric J.;  Canzian, Federico;  Severi, Gianluca;  Overvad, Kim;  Gunter, Marc J.;  Tumino, Rosario;  Svenson, Ulrika;  van Rij, Andre;  Baas, Annette F.;  Bown, Matthew J.;  Samani, Nilesh J.;  van t′  Hof, Femke N. G.;  Tromp, Gerard;  Jones, Gregory T.;  Kuivaniemi, Helena;  Elmore, James R.;  Johansson, Mattias;  Mckay, James;  Scelo, Ghislaine;  carreras-Torres, Robert;  Gaborieau, Valerie;  Brennan, Paul;  Bracci, Paige M.;  Neale, Rachel E.;  Olson, Sara H.;  Gallinger, Steven;  Li, Donghui;  Petersen, Gloria M.;  Risch, Harvey A.;  Klein, Alison P.;  Han, Jiali;  Abnet, Christian C.;  Freedman, Neal D.;  Taylor, Philip R.;  Maris, John M.;  Aben, Katja K.;  Kiemeney, Lambertus A.;  Vermeulen, Sita H.;  Wiencke, John K.;  Walsh, Kyle M.;  Wrensch, Margaret;  Rice, Terri;  Turnbull, Clare;  Litchfield, Kevin;  Paternoster, Lavinia;  Standl, Marie;  Abecasis, Goncalo R.;  SanGiovanni, John Paul;  Li, Yong;  Mijatovic, Vladan;  Sapkota, Yadav;  Low, Siew-Kee;  Zondervan, Krina T.;  Montgomery, Grant W.;  Nyholt, Dale R.;  van Heel, David A.;  Hunt, Karen;  Arking, Dan E.;  Ashar, Foram N.;  Sotoodehnia, Nona;  Woo, Daniel;  Rosand, Jonathan;  Comeau, Mary E.;  Brown, W. Mark;  Silverman, Edwin K.;  Hokanson, John E.;  Cho, Michael H.;  Hui, Jennie;  Ferreira, Manuel A.;  Thompson, Philip J.;  Morrison, Alanna C.;  Felix, Janine F.;  Smith, Nicholas L.;  Christiano, Angela M.;  Petukhova, Lynn;  Betz, Regina C.;  Fan, Xing;  Zhang, Xuejun;  Zhu, Caihong;  Langefeld, Carl D.;  Thompson, Susan D.;  Wang, Feijie;  Lin, Xu;  Schwartz, David A.;  Fingerlin, Tasha;  Rotter, Jerome I.;  Cotch, Mary Frances;  Jensen, Richard A.;  Munz, Matthias;  Dommisch, Henrik;  Schaefer, Arne S.;  Han, Fang;  Ollila, Hanna M.;  Hillary, Ryan P.;  Albagha, Omar;  Ralston, Stuart H.;  Zeng, Chenjie;  Zheng, Wei;  Shu, Xiao-Ou;  Reis, Andre;  Uebe, Steffen;  Hueffmeier, Ulrike;  Kawamura, Yoshiya;  Otowa, Takeshi;  Sasaki, Tsukasa;  Hibberd, Martin Lloyd;  Davila, Sonia;  Xie, Gang;  Siminovitch, Katherine;  Bei, Jin-Xin;  Zeng, Yi-Xin;  Foersti, Asta;  Chen, Bowang;  Landi, Stefano;  Franke, Andre;  Fischer, Annegret;  Ellinghaus, David;  Flores, Carlos;  Noth, Imre;  Ma, Shwu-Fan;  Foo, Jia Nee;  Liu, Jianjun;  Kim, Jong-Won;  Cox, David G.;  Delattre, Olivier;  Mirabeau, Olivier;  Skibola, Christine F.;  Tang, Clara S.;  Garcia-Barcelo, Merce;  Chang, Kai-Ping;  Su, Wen-Hui;  Chang, Yu-Sun;  Martin, Nicholas G.;  Gordon, Scott;  Wade, Tracey D.;  Lee, Chaeyoung;  Kubo, Michiaki;  Cha, Pei-Chieng;  Nakamura, Yusuke;  Levy, Daniel;  Kimura, Masayuki;  Hwang, Shih-Jen;  Hunt, Steven;  Spector, Tim;  Soranzo, Nicole;  Manichaikul, Aniw.;  Barr, Graham;  Kahali, Bratati;  Speliotes, Elizabeth;  Yerges-Armstrong, LauraM.;  Cheng, Ching-Yu;  Jonas, Jost B.;  Wong, Tien Yin;  Fogh, Isabella;  Lin, Kuang;  Powell, John F.;  Rice, Kenneth;  Relton, Caroline L.;  Martin, Richard M.;  Smith, George Davey;  Telomeres Mendelian Randomization;  Haycock, Philip C.(1,2)
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The clinical impact of non-obstructive chronic bronchitis in current and former smokers 期刊论文
RESPIRATORY MEDICINE, 2014, 卷号: 108, 期号: 3, 页码: 491-499
Authors:  Martinez, Carlos H.;  Kim, Victor;  Chen, Yahong;  Kazerooni, Ella A.;  Murray, Susan;  Criner, Gerard J.;  Curtis, Jeffrey L.;  Regan, Elizabeth A.;  Wan, Emily;  Hersh, Craig P.;  Silverman, Edwin K.;  Crapo, James D.;  Martinez, Fernando J.;  Han, MeiLan K.;  COPDGene Investigators
Favorite  |  View/Download:9/0  |  Submit date:2016/11/09
Cough  Quality Of Life  Gastroesophageal Reflux  Occupational Exposure  Gerd  Tobacco