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Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder 期刊论文
NATURE GENETICS, 2019, 卷号: 51, 期号: 1, 页码: 63-+
Authors:  Demontis, Ditte;  Walters, Raymond K.;  Martin, Joanna;  Mattheisen, Manuel;  Als, Thomas D.;  Agerbo, Esben;  Baldursson, Gisli;  Belliveau, Rich;  Bybjerg-Grauholm, Jonas;  Baekvad-Hansen, Marie;  Cerrato, Felecia;  Chambert, Kimberly;  Churchhouse, Claire;  Dumont, Ashley;  Eriksson, Nicholas;  Gandal, Michael;  Goldstein, Jacqueline I.;  Grasby, Katrina L.;  Grove, Jakob;  Gudmundsson, Olafur O.;  Hansen, Christine S.;  Hauberg, Mads Engel;  Hollegaard, Mads V.;  Howrigan, Daniel P.;  Huang, Hailiang;  Maller, Julian B.;  Martin, Alicia R.;  Martin, Nicholas G.;  Moran, Jennifer;  Pallesen, Jonatan;  Palmer, Duncan S.;  Pedersen, Carsten Bocker;  Pedersen, Marianne Giortz;  Poterba, Timothy;  Poulsen, Jesper Buchhave;  Ripke, Stephan;  Robinson, Elise B.;  Satterstrom, F. Kyle;  Stefansson, Hreinn;  Stevens, Christine;  Turley, Patrick;  Walters, G. Bragi;  Won, Hyejung;  Wright, Margaret J.;  Andreassen, Ole A.;  Asherson, Philip;  Burton, Christie L.;  Boomsma, Dorret I.;  Cormand, Bru;  Dalsgaard, Soren;  Franke, Barbara;  Gelernter, Joel;  Geschwind, Daniel;  Hakonarson, Hakon;  Haavik, Jan;  Kranzler, Henry R.;  Kuntsi, Jonna;  Langley, Kate;  Lesch, Klaus-Peter;  Middeldorp, Christel;  Reif, Andreas;  Rohde, Luis Augusto;  Roussos, Panos;  Schachar, Russell;  Sklar, Pamela;  Sonuga-Barke, Edmund J. S.;  Sullivan, Patrick F.;  Thapar, Anita;  Tung, Joyce Y.;  Waldman, Irwin D.;  Medland, Sarah E.;  Stefansson, Kari;  Nordentoft, Merete;  Hougaard, David M.;  Werge, Thomas;  Mors, Ole;  Mortensen, Preben Bo;  Daly, Mark J.;  Faraone, Stephen V.;  Borglum, Anders D.;  Neale, Benjamin M.;  Albayrak, Ozgur;  Anney, Richard J. L.;  Arranz, Maria Jesus;  Banaschewski, Tobias J.;  Bau, Claiton;  Biederman, Joseph;  Buitelaar, Jan K.;  Casas, Miguel;  Charach, Alice;  Crosbie, Jennifer;  Dempfle, Astrid;  Doyle, Alysa E.;  Ebstein, Richard P.;  Elia, Josephine;  Freitag, Christine;  Focker, Manuel;  Gill, Michael;  Grevet, Eugenio;  Hawi, Ziarih;  Hebebrand, Johannes;  Herpertz-Dahlmann, Beate;  Hervas, Amaia;  Hinney, Anke;  Hohmann, Sarah;  Holmans, Peter;  Hutz, Mara;  Ickowitz, Abel;  Johansson, Stefan;  Kent, Lindsey;  Kittel-Schneider, Sarah;  Lambregts-Rommelse, Nanda;  Lehmkuhl, Gerd;  Loo, Sandra K.;  McGough, James J.;  Meyer, Jobst;  Mick, Eric;  Middletion, Frank;  Miranda, Ana;  Mota, Nina Roth;  Mulas, Fernando;  Mulligan, Aisling;  Nelson, Freimer;  Nguyen, T. Trang;  Oades, Robert D.;  O′  Donovan, Michael C.;  Owen, Michael J.;  Palmason, Haukur;  Ramos-Quiroga, Josep Antoni;  Renner, Tobias J.;  Ribases, Marta;  Rietschel, Marcella;  Rivero, Olga;  Romanos, Jasmin;  Romanos, Marcel;  Rothenberger, Aribert;  Royers, Herbert;  Sanchez-Mora, Christina;  Scherag, Andre;  Schimmelmann, Benno G.;  Schafer, Helmut;  Sergeant, Joseph;  Sinzig, Judith;  Smalley, Susan L.;  Steinhausen, Hans-Christoph;  Thompson, Margaret;  Todorov, Alexandre;  Vasquez, Alejandro Arias;  Walitza, Susanne;  Wang, Yufeng;  Warnke, Andreas;  Williams, Nigel;  Witt, Stephanie H.;  Yang, Li;  Zayats, Tetyana;  Zhang-James, Yanli;  Smith, George Davey;  Davies, Gareth E.;  Ehli, Erik A.;  Evans, David M.;  Fedko, Iryna O.;  Greven, Corina U.;  Groen-Blokhuis, Maria M.;  Guxens, Monica;  Hammerschlag, Anke R.;  Hartman, Catharina A.;  Heinrich, Joachim;  Hottenga, Jouke Jan;  Hudziak, James;  Jugessur, Astanand;  Kemp, John P.;  Krapohl, Eva;  Murcia, Mario;  Myhre, Ronny;  Nolte, Ilja M.;  Nyholt, Dale R.;  Ormel, Johan;  Ouwens, Klaasjan G.;  Pappa, Irene;  Pennell, Craig E.;  Plomin, Robert;  Ring, Susan;  Standl, Marie;  Stergiakouli, Evie;  St Pourcain, Beate;  Stoltenberg, Camilla;  Sunyer, Jordi;  Thiering, Elisabeth;  Tiemeier, Henning;  Tiesler, Carla M. T.;  Timpson, Nicholas J.;  Trzaskowski, Maciej;  van der Most, Peter Johannes;  Vilor-Tejedor, Natalia;  Wang, Carol A.;  Whitehouse, Andrew J. O.;  Zhao, Huiying;  Agee, Michelle;  Alipanahi, Babak;  Auton, Adam;  Bell, Robert K.;  Bryc, Katarzyna;  Elson, Sarah L.;  Fontanillas, Pierre;  Furlotte, Nicholas A.;  Hinds, David A.;  Hromatka, Bethann S.;  Huber, Karen E.;  Kleinman, Aaron;  Litterman, Nadia K.;  McIntyre, Matthew H.;  Mountain, Joanna L.;  Northover, Carrie A. M.;  Pitts, Steven J.;  Sathirapongsasuti, J. Fah;  Sazonova, Olga V.;  Shelton, Janie F.;  Shringarpure, Suyash;  Tian, Chao;  Vacic, Vladimir;  Wilson, Catherine H.;  ADHD Working Grp Psychiat Genomics();  Early Lifecourse Genetic();  23andMe Res Team
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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders 期刊论文
AMERICAN JOURNAL OF HUMAN GENETICS, 2018, 卷号: 103, 期号: 5, 页码: 691-706
Authors:  Ligthart, Symen;  Vaez, Ahmad;  Vosa, Urmo;  Stathopoulou, Maria G.;  de Vries, Paul S.;  Prins, Bram P.;  Van der Most, Peter J.;  Tanaka, Toshiko;  Naderi, Elnaz;  Rose, Lynda M.;  Wu, Ying;  Karlsson, Robert;  Barbalic, Maja;  Lin, Honghuang;  Pool, Rene;  Zhu, Gu;  Mace, Aurelien;  Sidore, Carlo;  Trompet, Stella;  Mangino, Massimo;  Sabater-Lleal, Maria;  Kemp, John P.;  Abbasi, Ali;  Kacprowski, Tim;  Verweij, Niek;  Smith, Albert V.;  Huang, Tao;  Marzi, Carola;  Feitosa, Mary F.;  Lohman, Kurt K.;  Kleber, Marcus E.;  Milaneschi, Yuri;  Mueller, Christian;  Huq, Mahmudul;  Vlachopoulou, Efthymia;  Lyytikainen, Leo-Pekka;  Oldmeadow, Christopher;  Deelen, Joris;  Perola, Markus;  Zhao, Jing Hua;  Feenstra, Bjarke;  Amini, Marzyeh;  Lahti, Jari;  Schraut, Katharina E.;  Fornage, Myriam;  Suktitipat, Bhoom;  Chen, Wei-Min;  Li, Xiaohui;  Nutile, Teresa;  Malerba, Giovanni;  Luan, Jian′  an;  Bak, Tom;  Schork, Nicholas;  Del Greco, Fabiola M.;  Thiering, Elisabeth;  Mahajan, Anubha;  Marioni, Riccardo E.;  Mihailov, Evelin;  Eriksson, Joel;  Ozel, Ayse Bilge;  Zhang, Weihua;  Nethander, Maria;  Cheng, Yu-Ching;  Aslibekyan, Stella;  Ang, Wei;  Gandin, Ilaria;  Yengo, Loic;  Portas, Laura;  Kooperberg, Charles;  Hofer, Edith;  Rajan, Kumar B.;  Schurmann, Claudia;  den Hollander, Wouter;  Ahluwalia, Tarunveer S.;  Zhao, Jing;  Draisma, Harmen H. M.;  Ford, Ian;  Timpson, Nicholas;  Teumer, Alexander;  Huang, Hongyan;  Wahl, Simone;  Liu, YongMei;  Huang, Jie;  Uh, Hae-Won;  Geller, Frank;  Joshi, Peter K.;  Yanek, Lisa R.;  Trabetti, Elisabetta;  Lehne, Benjamin;  Vozzi, Diego;  Verbanck, Marie;  Biino, Ginevra;  Saba, Yasaman;  Meulenbelt, Ingrid;  O′  Connell, Jeff R.;  Laakso, Markku;  Giulianini, Franco;  Magnusson, Patrik K. E.;  Ballantyne, Christie M.;  Hottenga, Jouke Jan;  Montgomery, GrantW.;  Rivadineira, Fernando;  Rueedi, Rico;  Steri, Maristella;  Herzig, Karl-Heinz;  Stott, David J.;  Menni, Cristina;  Franberg, Mattias;  St Pourcain, Beate;  Felix, Stephan B.;  Pers, Tune H.;  Bakker, Stephan J. L.;  Kraft, Peter;  Peters, Annette;  Vaidya, Dhananjay;  Delgado, Graciela;  Smit, Johannes H.;  Grossmann, Vera;  Sinisalo, Juha;  Seppala, Ilkka;  Williams, Stephen R.;  Holliday, Elizabeth G.;  Moed, Matthijs;  Langenberg, Claudia;  Raikkonen, Katri;  Ding, Jingzhong;  Campbell, Harry;  Sale, Michele M.;  Chen, Yii-Der I.;  James, Alan L.;  Ruggiero, Daniela;  Soranzo, Nicole;  Hartman, Catharina A.;  Smith, Erin N.;  Berenson, Gerald S.;  Fuchsberger, Christian;  Hernandez, Dena;  Tiesler, Carla M. T.;  Giedraitis, Vilmantas;  Liewald, David;  Fischer, Krista;  Mellstrom, Dan;  Larsson, Anders;  Wang, Yunmei;  Scott, William R.;  Lorentzon, Matthias;  Beilby, John;  Ryan, Kathleen A.;  Pennell, Craig E.;  Vuckovic, Dragana;  Balkau, Beverly;  Concas, Maria Pina;  Schmidt, Reinhold;  de Leon, Carlos F. Mendes;  Bottinger, Erwin P.;  Kloppenburg, Margreet;  Paternoster, Lavinia;  Boehnke, Michael;  Musk, A. W.;  Willemsen, Gonneke;  Evans, David M.;  Madden, Pamela A. F.;  Kahonen, Mika;  Kutalik, Zoltan;  Zoledziewska, Magdalena;  Karhunen, Ville;  Kritchevsky, Stephen B.;  Sattar, Naveed;  Lachance, Genevieve;  Clarke, Robert;  Harris, Tamara B.;  Raitakari, Olli T.;  Attia, John R.;  Van Heemst, Diana;  Kajantie, Eero;  Sorice, Rossella;  Gambaro, Giovanni;  Scott, Robert A.;  Hicks, Andrew A.;  Ferrucci, Luigi;  Standl, Marie;  Lindgren, Cecilia M.;  Starr, John M.;  Karlsson, Magnus;  Lind, Lars;  Li, Jun Z.;  Chambers, John C.;  Mori, Trevor A.;  de Geus, Eco J. C. N.;  Heath, Andrew C.;  Martin, Nicholas G.;  Auvinen, Juha;  Buckley, Brendan M.;  de Craen, Anton J. M.;  Waldenberger, Melanie;  Strauch, Konstantin;  Meitinger, Thomas;  Scott, Rodney J.;  McEvoy, Mark;  Beekman, Marian;  Bombieri, Cristina;  Ridker, Paul M.;  Mohlke, Karen L.;  Pedersen, Nancy L.;  Morrison, Alanna C.;  Boomsma, Dorret I.;  Whitfield, John B.;  Strachan, David P.;  Hofman, Albert;  Vollenweider, Peter;  Cucca, Francesco;  Jarvelin, Marjo-Riitta;  Jukema, J. Wouter;  Spector, Tim D.;  Hamsten, Anders;  Zeller, Tanja;  Uitterlinden, Andre G.;  Nauck, Matthias;  Gudnason, Vilmundur;  Qi, Lu;  Grallert, Harald;  Borecki, Ingrid B.;  Rotter, Jerome I.;  Maerz, Winfried;  Wild, Philipp S.;  Lokki, Marja-Liisa;  Boyle, Michael;  Salomaa, Veikko;  Melbye, Mads;  Eriksson, Johan G.;  Wilson, James F.;  Penninx, Brenda W. J. H.;  Becker, Diane M.;  Worrall, Bradford B.;  Gibson, Greg;  Krauss, Ronald M.;  Ciullo, Marina;  Zaza, Gianluigi;  Wareham, Nicholas J.;  Oldehinkel, Albertine J.;  Palmer, Lyle J.;  Murray, Sarah S.;  Pramstaller, Peter P.;  Bandinelli, Stefania;  Heinrich, Joachim;  Ingelsson, Erik;  Deary, Ian J.;  Magi, Reedik;  Vandenput, Liesbeth;  van der Harst, Pim;  Desch, Karl C.;  Kooner, Jaspal S.;  Ohlsson, Claes;  Hayward, Caroline;  Lehtimaki, Terho;  Shuldiner, Alan R.;  Arnett, Donna K.;  Beilin, Lawrence J.;  Robino, Antonietta;  Froguel, Philippe;  Pirastu, Mario;  Jess, Tine;  Koenig, Wolfgang;  Loos, Ruth J. F.;  Evans, Denis A.;  Schmidt, Helena;  Smith, George Davey;  Slagboom, P. Eline;  Eiriksdottir, Gudny;  Morris, Andrew P.;  Psaty, Bruce M.;  Tracy, Russell P.;  Nolte, Ilja M.;  Boerwinkle, Eric;  Visvikis-Siest, Sophie;  Reiner, Alex P.;  Gross, Myron;  Bis, Joshua C.;  Franke, Lude;  Franco, Oscar H.;  Benjamin, Emelia J.;  Chasman, Daniel I.;  Dupuis, Josee;  Snieder, Harold;  Dehghan, Abbas;  Alizadeh, Behrooz Z.;  LifeLines Cohort Study;  CHARGE Inflammation Working Grp();  Dehghan, Abbas(1,191);  Alizadeh, Behrooz Z.(2)
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Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study 期刊论文
JAMA ONCOLOGY, 2017, 卷号: 3, 期号: 5, 页码: 636-651
Authors:  Haycock, Philip C.;  Burgess, Stephen;  Nounu, Aayah;  Zheng, Jie;  Okoli, George N.;  Bowden, Jack;  Wade, Kaitlin Hazel;  Timpson, Nicholas J.;  Evans, David M.;  Willeit, Peter;  Aviv, Abraham;  Gaunt, Tomr.;  Hemani, Gibran;  Mangino, Massimo;  Ellis, Hayley Patricia;  Kurian, Kathreena M.;  Pooley, Karen A.;  Eeles, Rosalind A.;  Lee, Jeffrey E.;  Fang, Shenying;  Chen, Wei V.;  Law, Matthew H.;  Bowdler, Lisa M.;  Iles, Mark M.;  Yang, Qiong;  Worrall, Bradford B.;  Markus, Hugh Stephen;  Hung, Rayjean J.;  Amos, Chris I.;  Spurdle, Amanda B.;  Thompson, Deborah J.;  O′  Mara, Tracy A.;  Wolpin, Brian;  Amundadottir, Laufey;  Stolzenberg-Solomon, Rachael;  Trichopoulou, Antonia;  Onland-Moret, Charlotte;  Lund, Eiliv;  Duell, Eric J.;  Canzian, Federico;  Severi, Gianluca;  Overvad, Kim;  Gunter, Marc J.;  Tumino, Rosario;  Svenson, Ulrika;  van Rij, Andre;  Baas, Annette F.;  Bown, Matthew J.;  Samani, Nilesh J.;  van t′  Hof, Femke N. G.;  Tromp, Gerard;  Jones, Gregory T.;  Kuivaniemi, Helena;  Elmore, James R.;  Johansson, Mattias;  Mckay, James;  Scelo, Ghislaine;  carreras-Torres, Robert;  Gaborieau, Valerie;  Brennan, Paul;  Bracci, Paige M.;  Neale, Rachel E.;  Olson, Sara H.;  Gallinger, Steven;  Li, Donghui;  Petersen, Gloria M.;  Risch, Harvey A.;  Klein, Alison P.;  Han, Jiali;  Abnet, Christian C.;  Freedman, Neal D.;  Taylor, Philip R.;  Maris, John M.;  Aben, Katja K.;  Kiemeney, Lambertus A.;  Vermeulen, Sita H.;  Wiencke, John K.;  Walsh, Kyle M.;  Wrensch, Margaret;  Rice, Terri;  Turnbull, Clare;  Litchfield, Kevin;  Paternoster, Lavinia;  Standl, Marie;  Abecasis, Goncalo R.;  SanGiovanni, John Paul;  Li, Yong;  Mijatovic, Vladan;  Sapkota, Yadav;  Low, Siew-Kee;  Zondervan, Krina T.;  Montgomery, Grant W.;  Nyholt, Dale R.;  van Heel, David A.;  Hunt, Karen;  Arking, Dan E.;  Ashar, Foram N.;  Sotoodehnia, Nona;  Woo, Daniel;  Rosand, Jonathan;  Comeau, Mary E.;  Brown, W. Mark;  Silverman, Edwin K.;  Hokanson, John E.;  Cho, Michael H.;  Hui, Jennie;  Ferreira, Manuel A.;  Thompson, Philip J.;  Morrison, Alanna C.;  Felix, Janine F.;  Smith, Nicholas L.;  Christiano, Angela M.;  Petukhova, Lynn;  Betz, Regina C.;  Fan, Xing;  Zhang, Xuejun;  Zhu, Caihong;  Langefeld, Carl D.;  Thompson, Susan D.;  Wang, Feijie;  Lin, Xu;  Schwartz, David A.;  Fingerlin, Tasha;  Rotter, Jerome I.;  Cotch, Mary Frances;  Jensen, Richard A.;  Munz, Matthias;  Dommisch, Henrik;  Schaefer, Arne S.;  Han, Fang;  Ollila, Hanna M.;  Hillary, Ryan P.;  Albagha, Omar;  Ralston, Stuart H.;  Zeng, Chenjie;  Zheng, Wei;  Shu, Xiao-Ou;  Reis, Andre;  Uebe, Steffen;  Hueffmeier, Ulrike;  Kawamura, Yoshiya;  Otowa, Takeshi;  Sasaki, Tsukasa;  Hibberd, Martin Lloyd;  Davila, Sonia;  Xie, Gang;  Siminovitch, Katherine;  Bei, Jin-Xin;  Zeng, Yi-Xin;  Foersti, Asta;  Chen, Bowang;  Landi, Stefano;  Franke, Andre;  Fischer, Annegret;  Ellinghaus, David;  Flores, Carlos;  Noth, Imre;  Ma, Shwu-Fan;  Foo, Jia Nee;  Liu, Jianjun;  Kim, Jong-Won;  Cox, David G.;  Delattre, Olivier;  Mirabeau, Olivier;  Skibola, Christine F.;  Tang, Clara S.;  Garcia-Barcelo, Merce;  Chang, Kai-Ping;  Su, Wen-Hui;  Chang, Yu-Sun;  Martin, Nicholas G.;  Gordon, Scott;  Wade, Tracey D.;  Lee, Chaeyoung;  Kubo, Michiaki;  Cha, Pei-Chieng;  Nakamura, Yusuke;  Levy, Daniel;  Kimura, Masayuki;  Hwang, Shih-Jen;  Hunt, Steven;  Spector, Tim;  Soranzo, Nicole;  Manichaikul, Aniw.;  Barr, Graham;  Kahali, Bratati;  Speliotes, Elizabeth;  Yerges-Armstrong, LauraM.;  Cheng, Ching-Yu;  Jonas, Jost B.;  Wong, Tien Yin;  Fogh, Isabella;  Lin, Kuang;  Powell, John F.;  Rice, Kenneth;  Relton, Caroline L.;  Martin, Richard M.;  Smith, George Davey;  Telomeres Mendelian Randomization;  Haycock, Philip C.(1,2)
Favorite  |  View/Download:6/0  |  Submit date:2018/06/22