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Are Environmental Factors for Atopic Eczema in ISAAC Phase Three due to Reverse Causation? 期刊论文
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2019, 卷号: 139, 期号: 5, 页码: 1023-1036
Authors:  Rutter, Charlotte E.;  Silverwood, Richard J.;  Williams, Hywel C.;  Ellwood, Philippa;  Asher, Innes;  Garcia-Marcos, Luis;  Strachan, David P.;  Pearce, Neil;  Langan, Sinead M.;  Ait-Khaled, N.;  Anderson, H. R.;  Asher, M., I;  Beasley, R.;  Bjorksten, B.;  Brunekreef, B.;  Crane, J.;  Ellwood, P.;  Flohr, C.;  Foliaki, S.;  Forastiere, F.;  Garcia-Marcos, L.;  Keil, U.;  Lai, C. K. W.;  Mallol, J.;  Mitchell, E. A.;  Montefort, S.;  Odhiambo, J.;  Pearce, N.;  Robertson, C. F.;  Stewart, A. W.;  Strachan, D.;  von Mutius, E.;  Weiland, S. K.;  Weinmayr, G.;  Williams, H. C.;  Wong, G.;  Clayton, T. O.;  Ellwood, E.;  Baena-Cagnani, C. E.;  Gomez, M.;  Howitt, M. E.;  Weyler, J.;  Pinto-Vargas, R.;  da Cunha, A. J.;  de Freitas Souza, L.;  Kuaban, C.;  Ferguson, A.;  Rennie, D.;  Standring, P.;  Aguilar, P.;  Amarales, L.;  Benavides, L. A.;  Contreras, A.;  Chen, Y-Z;  Kunii, O.;  Pan, Q. Li;  Zhong, N. S.;  Aristizabal, G.;  Cepeda, A. M.;  Ordonez, G. A.;  Bustos, C.;  Riikjarv, M-A;  Melaku, K.;  Sa′  aga-Banuve, R.;  Pekkanen, J.;  Hypolite, I. E.;  Novak, Z.;  Zsigmond, G.;  Awasthi, S.;  Bhave, S.;  Hanumante, N. M.;  Jain, K. C.;  Joshi, M. K.;  Khatav, V. A.;  Mantri, S. N.;  Pherwani, A., V;  Rego, S.;  Sabir, M.;  Salvi, S.;  Setty, G.;  Sharma, S. K.;  Singh, V;  Sukumaran, T.;  Babu, P. S. Suresh;  Kartasasmita, C. B.;  Konthen, P.;  Suprihati, W.;  Masjedi, M. R.;  Steriu, A.;  Koffi, B. N.;  Odajima, H.;  al-Momen, J. A.;  Imanalieva, C.;  Kudzyte, J.;  Quah, B. S.;  Teh, K. H.;  Baeza-Bacab, M.;  Barragan-Meijueiro, M.;  Del-Rio-Navarro, B. E.;  Garcia-Almaraz, R.;  Gonzalez-Diaz, S. N.;  Linares-Zapien, F. J.;  Merida-Palacio, J., V;  Ramirez-Chanona, N.;  Romero-Tapia, S.;  Romieu, I;  Bouayad, Z.;  MacKay, R.;  Moyes, C.;  Pattemore, P.;  Onadeko, B. O.;  Cukier, G.;  Chiarella, P.;  Cua-Lim, F.;  Breborowicz, A.;  Sole, D.;  Sears, M.;  Aguirre, V;  Barba, S.;  Shah, J.;  Baratawidjaja, K.;  Nishima, S.;  de Bruyne, J.;  Tuuau-Potoi, N.;  Lai, C. K.;  Lee, B. W.;  El Sony, A.;  Anderson, R.;  ISAAC Phase Three Study Grp
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EARLY-LIFE EXPOSURE  CHILDHOOD ISAAC  GLOBAL ANALYSIS  FAMILY IMPACT  BIRTH-WEIGHT  ASTHMA  RHINOCONJUNCTIVITIS  ALLERGIES  RISK  SYMPTOMS  
Are environmental risk factors for current wheeze in the International Study of Asthma and Allergies in Childhood (ISAAC) phase three due to reverse causation? 期刊论文
CLINICAL AND EXPERIMENTAL ALLERGY, 2019, 卷号: 49, 期号: 4, 页码: 430-441
Authors:  Silverwood, Richard J.;  Rutter, Charlotte E.;  Mitchell, Edwin A.;  Asher, M. Innes;  Garcia-Marcos, Luis;  Strachan, David P.;  Pearce, Neil;  Ait-Khaled, N.;  Anderson, H. R.;  Asher, M. I.;  Beasley, R.;  Bjorksten, B.;  Brunekreef, B.;  Crane, J.;  Ellwood, P.;  Flohr, C.;  Foliaki, S.;  Forastiere, F.;  Garcia-Marcos, L.;  Keil, U.;  Lai, C. K. W.;  Mallol, J.;  Mitchell, E. A.;  Montefort, S.;  Odhiambo, J.;  Pearce, N.;  Robertson, C. F.;  Stewart, A. W.;  Strachan, D.;  von Mutius, E.;  Weiland, S. K.;  Weinmayr, G.;  Williams, H. C.;  Wong, G.;  Asher, M. I.;  Clayton, T. O.;  Ellwood, P.;  Mitchell, E. A.;  Stewart, A. W.;  Baena-Cagnani, C. E.;  Gomez, M.;  Howitt, M. E.;  Weyler, J.;  Pinto-Vargas, R.;  da Cunha, A. J.;  de Freitas Souza, L.;  Kuaban, C.;  Ferguson, A.;  Rennie, D.;  Standring, P.;  Aguilar, P.;  Amarales, L.;  Benavides, L. A.;  Contreras, A.;  Chen, Y-Z;  Kunii, O.;  Pan, Li;  Zhong, N. S.;  Aristizabal, G.;  Cepeda, A. M.;  Ordonez, G. A.;  Bustos, C.;  Riikjarv, M-A;  Melaku, K.;  Sa′  aga-Banuve, R.;  Pekkanen, J.;  Hypolite, I. E.;  Novak, Z.;  Zsigmond, G.;  Awasthi, S.;  Bhave, S.;  Hanumante, N. M.;  Jain, K. C.;  Joshi, M. K.;  Khatav, V. A.;  Mantri, S. N.;  Pherwani, A. V.;  Rego, S.;  Sabir, M.;  Salvi, S.;  Setty, G.;  Sharma, S. K.;  Singh, V.;  Sukumaran, T.;  Babu, P. S. Suresh;  Kartasasmita, C. B.;  Konthen, P.;  Suprihati, W.;  Masjedi, M. R.;  Steriu, A.;  Koffi, B. N.;  Odajima, H.;  al-Momen, J. A.;  Imanalieva, C.;  Kudzyte, J.;  Quah, B. S.;  Teh, K. H.;  Montefort, S.;  Baeza-Bacab, M.;  Barragan-Meijueiro, M.;  Del-Rio-Navarro, B. E.;  Garcia-Almaraz, R.;  Gonzalez-Diaz, S. N.;  Linares-Zapien, F. J.;  Merida-Palacio, J. V.;  Ramirez-Chanona, N.;  Romero-Tapia, S.;  Romieu, I.;  Bouayad, Z.;  Asher, M. I.;  MacKay, R.;  Moyes, C.;  Pattemore, P.;  Pearce, N.;  Onadeko, B. O.;  Cukier, G.;  Chiarella, P.;  Cua-Lim, F.;  Breborowicz, A.;  Lis, G.;  Camara, R.;  Chiera, M. L.;  Lopes dos Santos, J. M.;  Nunes, C.;  Pinto, J. Rosado;  Vlaski, E.;  Fuimaono, P.;  Pisi, V.;  Goh, D. Y.;  Zar, H. J.;  Lee, H. B.;  Blanco-Quiros, A.;  Busquets, R. M.;  Carvajal-Uruena, I.;  Garcia-Hernandez, G.;  Garcia-Marcos, L.;  Gonzalez Diaz, C.;  Lopez-Silvarrey, A.;  Morales-Suarez-Varela, M.;  Perez-Yarza, E. G.;  Musa, O. A.;  Al-Rawas, O.;  Mohammad, S.;  Mohammad, Y.;  Tabbah, K.;  Huang, J. L.;  Kao, C. C.;  Trakultivakorn, M.;  Vichyanond, P.;  Iosefa, T.;  Burr, M.;  Strachan, D.;  Holgado, D.;  Lapides, M. C.;  Windom, H. H.;  Aldrey, O.;  Sole, D.;  Sears, M.;  Aguirre, V.;  Barba, S.;  Shah, J.;  Baratawidjaja, K.;  Nishima, S.;  de Bruyne, J.;  Tuuau-Potoi, N.;  Lai, C. K.;  Lee, B. W.;  El Sony, A.;  Anderson, R.;  ISAAC Phase Three Study Grp;  ISAAC Int Data Ctr;  ISAAC Principal Investigators;  ISAAC Natl Coordinators Not
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asthma  GLOBAL FINDINGS  environment and hygiene hypothesis  RHINOCONJUNCTIVITIS  epidemiology  ECZEMA  SYMPTOMS  PREVALENCE  CHILDREN  ASSOCIATION  RATIONALE  EXPOSURE  INFANCY  
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries 期刊论文
NATURE GENETICS, 2019, 卷号: 51, 期号: 3, 页码: 481-+
Authors:  Shrine, Nick;  Guyatt, Anna L.;  Erzurumluoglu, A. Mesut;  Jackson, Victoria E.;  Hobbs, Brian D.;  Melbourne, Carl A.;  Batini, Chiara;  Fawcett, Katherine A.;  Song, Kijoung;  Sakornsakolpat, Phuwanat;  Li, Xingnan;  Boxall, Ruth;  Reeve, Nicola F.;  Obeidat, Ma′  en;  Zhao, Jing Hua;  Wielscher, Matthias;  Weiss, Stefan;  Kentistou, Katherine A.;  Cook, James P.;  Sun, Benjamin B.;  Zhou, Jian;  Hui, Jennie;  Karrasch, Stefan;  Imboden, Medea;  Harris, Sarah E.;  Marten, Jonathan;  Enroth, Stefan;  Kerr, Shona M.;  Surakka, Ida;  Vitart, Veronique;  Lehtimaki, Terho;  Allen, Richard J.;  Bakke, Per S.;  Beaty, Terri H.;  Bleecker, Eugene R.;  Bosse, Yohan;  Brandsma, Corry-Anke;  Chen, Zhengming;  Crapo, James D.;  Danesh, John;  DeMeo, Dawn L.;  Dudbridge, Frank;  Ewert, Ralf;  Gieger, Christian;  Gulsvik, Amund;  Hansell, Anna L.;  Hao, Ke;  Hoffman, Joshua D.;  Hokanson, John E.;  Homuth, Georg;  Joshi, Peter K.;  Joubert, Philippe;  Langenberg, Claudia;  Li, Xuan;  Li, Liming;  Lin, Kuang;  Lind, Lars;  Locantore, Nicholas;  Luan, Jian′  an;  Mahajan, Anubha;  Maranville, Joseph C.;  Murray, Alison;  Nickle, David C.;  Packer, Richard;  Parker, Margaret M.;  Paynton, Megan L.;  Porteous, David J.;  Prokopenko, Dmitry;  Qiao, Dandi;  Rawal, Rajesh;  Runz, Heiko;  Sayers, Ian;  Sin, Don D.;  Smith, Blair H.;  Artigas, Maria Soler;  Sparrow, David;  Tal-Singer, Ruth;  Timmers, Paul R. H. J.;  Van den Berge, Maarten;  Whittaker, John C.;  Woodruff, Prescott G.;  Verges-Armstrong, Laura M.;  Troyanskaya, Olga G.;  Raitakari, Olli T.;  Kahonenn, Mika;  Polasek, Ozren;  Gyllensten, Ulf;  Rudan, Igor;  Deary, Ian J.;  Probst-Hensch, Nicole M.;  Schulz, Holger;  James, Alan L.;  Wilson, James F.;  Stubbe, Beate;  Zeggini, Eleftheria;  Jarvelin, Marjo-Riitta;  Wareham, Nick;  Silverman, Edwin K.;  Hayward, Caroline;  Morris, Andrew P.;  Butterworth, Adam S.;  Scott, Robert A.;  Walters, Robin G.;  Meyers, Deborah A.;  Cho, Michael H.;  Strachan, David P.;  Hall, Ian P.;  Tobin, Martin D.;  Wain, Louise, V;  Understanding Soc Sci Grp()
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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders 期刊论文
AMERICAN JOURNAL OF HUMAN GENETICS, 2018, 卷号: 103, 期号: 5, 页码: 691-706
Authors:  Ligthart, Symen;  Vaez, Ahmad;  Vosa, Urmo;  Stathopoulou, Maria G.;  de Vries, Paul S.;  Prins, Bram P.;  Van der Most, Peter J.;  Tanaka, Toshiko;  Naderi, Elnaz;  Rose, Lynda M.;  Wu, Ying;  Karlsson, Robert;  Barbalic, Maja;  Lin, Honghuang;  Pool, Rene;  Zhu, Gu;  Mace, Aurelien;  Sidore, Carlo;  Trompet, Stella;  Mangino, Massimo;  Sabater-Lleal, Maria;  Kemp, John P.;  Abbasi, Ali;  Kacprowski, Tim;  Verweij, Niek;  Smith, Albert V.;  Huang, Tao;  Marzi, Carola;  Feitosa, Mary F.;  Lohman, Kurt K.;  Kleber, Marcus E.;  Milaneschi, Yuri;  Mueller, Christian;  Huq, Mahmudul;  Vlachopoulou, Efthymia;  Lyytikainen, Leo-Pekka;  Oldmeadow, Christopher;  Deelen, Joris;  Perola, Markus;  Zhao, Jing Hua;  Feenstra, Bjarke;  Amini, Marzyeh;  Lahti, Jari;  Schraut, Katharina E.;  Fornage, Myriam;  Suktitipat, Bhoom;  Chen, Wei-Min;  Li, Xiaohui;  Nutile, Teresa;  Malerba, Giovanni;  Luan, Jian′  an;  Bak, Tom;  Schork, Nicholas;  Del Greco, Fabiola M.;  Thiering, Elisabeth;  Mahajan, Anubha;  Marioni, Riccardo E.;  Mihailov, Evelin;  Eriksson, Joel;  Ozel, Ayse Bilge;  Zhang, Weihua;  Nethander, Maria;  Cheng, Yu-Ching;  Aslibekyan, Stella;  Ang, Wei;  Gandin, Ilaria;  Yengo, Loic;  Portas, Laura;  Kooperberg, Charles;  Hofer, Edith;  Rajan, Kumar B.;  Schurmann, Claudia;  den Hollander, Wouter;  Ahluwalia, Tarunveer S.;  Zhao, Jing;  Draisma, Harmen H. M.;  Ford, Ian;  Timpson, Nicholas;  Teumer, Alexander;  Huang, Hongyan;  Wahl, Simone;  Liu, YongMei;  Huang, Jie;  Uh, Hae-Won;  Geller, Frank;  Joshi, Peter K.;  Yanek, Lisa R.;  Trabetti, Elisabetta;  Lehne, Benjamin;  Vozzi, Diego;  Verbanck, Marie;  Biino, Ginevra;  Saba, Yasaman;  Meulenbelt, Ingrid;  O′  Connell, Jeff R.;  Laakso, Markku;  Giulianini, Franco;  Magnusson, Patrik K. E.;  Ballantyne, Christie M.;  Hottenga, Jouke Jan;  Montgomery, GrantW.;  Rivadineira, Fernando;  Rueedi, Rico;  Steri, Maristella;  Herzig, Karl-Heinz;  Stott, David J.;  Menni, Cristina;  Franberg, Mattias;  St Pourcain, Beate;  Felix, Stephan B.;  Pers, Tune H.;  Bakker, Stephan J. L.;  Kraft, Peter;  Peters, Annette;  Vaidya, Dhananjay;  Delgado, Graciela;  Smit, Johannes H.;  Grossmann, Vera;  Sinisalo, Juha;  Seppala, Ilkka;  Williams, Stephen R.;  Holliday, Elizabeth G.;  Moed, Matthijs;  Langenberg, Claudia;  Raikkonen, Katri;  Ding, Jingzhong;  Campbell, Harry;  Sale, Michele M.;  Chen, Yii-Der I.;  James, Alan L.;  Ruggiero, Daniela;  Soranzo, Nicole;  Hartman, Catharina A.;  Smith, Erin N.;  Berenson, Gerald S.;  Fuchsberger, Christian;  Hernandez, Dena;  Tiesler, Carla M. T.;  Giedraitis, Vilmantas;  Liewald, David;  Fischer, Krista;  Mellstrom, Dan;  Larsson, Anders;  Wang, Yunmei;  Scott, William R.;  Lorentzon, Matthias;  Beilby, John;  Ryan, Kathleen A.;  Pennell, Craig E.;  Vuckovic, Dragana;  Balkau, Beverly;  Concas, Maria Pina;  Schmidt, Reinhold;  de Leon, Carlos F. Mendes;  Bottinger, Erwin P.;  Kloppenburg, Margreet;  Paternoster, Lavinia;  Boehnke, Michael;  Musk, A. W.;  Willemsen, Gonneke;  Evans, David M.;  Madden, Pamela A. F.;  Kahonen, Mika;  Kutalik, Zoltan;  Zoledziewska, Magdalena;  Karhunen, Ville;  Kritchevsky, Stephen B.;  Sattar, Naveed;  Lachance, Genevieve;  Clarke, Robert;  Harris, Tamara B.;  Raitakari, Olli T.;  Attia, John R.;  Van Heemst, Diana;  Kajantie, Eero;  Sorice, Rossella;  Gambaro, Giovanni;  Scott, Robert A.;  Hicks, Andrew A.;  Ferrucci, Luigi;  Standl, Marie;  Lindgren, Cecilia M.;  Starr, John M.;  Karlsson, Magnus;  Lind, Lars;  Li, Jun Z.;  Chambers, John C.;  Mori, Trevor A.;  de Geus, Eco J. C. N.;  Heath, Andrew C.;  Martin, Nicholas G.;  Auvinen, Juha;  Buckley, Brendan M.;  de Craen, Anton J. M.;  Waldenberger, Melanie;  Strauch, Konstantin;  Meitinger, Thomas;  Scott, Rodney J.;  McEvoy, Mark;  Beekman, Marian;  Bombieri, Cristina;  Ridker, Paul M.;  Mohlke, Karen L.;  Pedersen, Nancy L.;  Morrison, Alanna C.;  Boomsma, Dorret I.;  Whitfield, John B.;  Strachan, David P.;  Hofman, Albert;  Vollenweider, Peter;  Cucca, Francesco;  Jarvelin, Marjo-Riitta;  Jukema, J. Wouter;  Spector, Tim D.;  Hamsten, Anders;  Zeller, Tanja;  Uitterlinden, Andre G.;  Nauck, Matthias;  Gudnason, Vilmundur;  Qi, Lu;  Grallert, Harald;  Borecki, Ingrid B.;  Rotter, Jerome I.;  Maerz, Winfried;  Wild, Philipp S.;  Lokki, Marja-Liisa;  Boyle, Michael;  Salomaa, Veikko;  Melbye, Mads;  Eriksson, Johan G.;  Wilson, James F.;  Penninx, Brenda W. J. H.;  Becker, Diane M.;  Worrall, Bradford B.;  Gibson, Greg;  Krauss, Ronald M.;  Ciullo, Marina;  Zaza, Gianluigi;  Wareham, Nicholas J.;  Oldehinkel, Albertine J.;  Palmer, Lyle J.;  Murray, Sarah S.;  Pramstaller, Peter P.;  Bandinelli, Stefania;  Heinrich, Joachim;  Ingelsson, Erik;  Deary, Ian J.;  Magi, Reedik;  Vandenput, Liesbeth;  van der Harst, Pim;  Desch, Karl C.;  Kooner, Jaspal S.;  Ohlsson, Claes;  Hayward, Caroline;  Lehtimaki, Terho;  Shuldiner, Alan R.;  Arnett, Donna K.;  Beilin, Lawrence J.;  Robino, Antonietta;  Froguel, Philippe;  Pirastu, Mario;  Jess, Tine;  Koenig, Wolfgang;  Loos, Ruth J. F.;  Evans, Denis A.;  Schmidt, Helena;  Smith, George Davey;  Slagboom, P. Eline;  Eiriksdottir, Gudny;  Morris, Andrew P.;  Psaty, Bruce M.;  Tracy, Russell P.;  Nolte, Ilja M.;  Boerwinkle, Eric;  Visvikis-Siest, Sophie;  Reiner, Alex P.;  Gross, Myron;  Bis, Joshua C.;  Franke, Lude;  Franco, Oscar H.;  Benjamin, Emelia J.;  Chasman, Daniel I.;  Dupuis, Josee;  Snieder, Harold;  Dehghan, Abbas;  Alizadeh, Behrooz Z.;  LifeLines Cohort Study;  CHARGE Inflammation Working Grp();  Dehghan, Abbas(1,191);  Alizadeh, Behrooz Z.(2)
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